Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

Contextual Factors Working Group

doi:10.3899/jrheum.181081

Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

Contextual Factors Working Group

Parker Instituttet

12 Citationer (Scopus)

Abstract

OBJECTIVE: The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.

METHODS: During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.

RESULTS: A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.

CONCLUSION: The identified important contextual factor domains may be considered a provisional list pending further research.

Originalsprog	Engelsk
Tidsskrift	Journal of Rheumatology
Vol/bind	46
Udgave nummer	9
Sider (fra-til)	1159-1163
Antal sider	5
ISSN	0315-162X
DOI	https://doi.org/10.3899/jrheum.181081
Status	Udgivet - sep. 2019

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10.3899/jrheum.181081

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@article{04b8647f887944bb961360e71336c16c,

title = "Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative",

abstract = "OBJECTIVE: The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.METHODS: During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.RESULTS: A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.CONCLUSION: The identified important contextual factor domains may be considered a provisional list pending further research.",

keywords = "Clinical trials, Omeract, Outcomes, Rheumatic diseases",

author = "Nielsen, \{Sabrina M\} and Peter Tugwell and \{de Wit\}, \{Maarten P T\} and Maarten Boers and Beaton, \{Dorcas E\} and Woodworth, \{Thasia G\} and Reuben Escorpizo and Beverley Shea and Karine Toupin-April and Francis Guillemin and Vibeke Strand and Singh, \{Jasvinder A\} and Margreet Kloppenburg and Furst, \{Daniel E\} and Wells, \{George A\} and Smolen, \{Josef S\} and Richard Vesel{\'y} and Annelies Boonen and Helene Storgaard and Marieke Voshaar and Lyn March and Robin Christensen and \{Contextual Factors Working Group\}",

year = "2019",

month = sep,

doi = "10.3899/jrheum.181081",

language = "English",

volume = "46",

pages = "1159--1163",

journal = "Journal of Rheumatology",

issn = "0315-162X",

publisher = "Journal of Rheumatology",

number = "9",

}

TY - JOUR

T1 - Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology

T2 - Results from an OMERACT Initiative

AU - Nielsen, Sabrina M

AU - Tugwell, Peter

AU - de Wit, Maarten P T

AU - Boers, Maarten

AU - Beaton, Dorcas E

AU - Woodworth, Thasia G

AU - Escorpizo, Reuben

AU - Shea, Beverley

AU - Toupin-April, Karine

AU - Guillemin, Francis

AU - Strand, Vibeke

AU - Singh, Jasvinder A

AU - Kloppenburg, Margreet

AU - Furst, Daniel E

AU - Wells, George A

AU - Smolen, Josef S

AU - Veselý, Richard

AU - Boonen, Annelies

AU - Storgaard, Helene

AU - Voshaar, Marieke

AU - March, Lyn

AU - Christensen, Robin

AU - Contextual Factors Working Group

PY - 2019/9

Y1 - 2019/9

N2 - OBJECTIVE: The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.METHODS: During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.RESULTS: A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.CONCLUSION: The identified important contextual factor domains may be considered a provisional list pending further research.

AB - OBJECTIVE: The Contextual Factors Working Group aims to provide guidance on addressing contextual factors in rheumatology trials within OMERACT.METHODS: During the Special Interest Group session at OMERACT 2018, preliminary results were presented from a case scenario survey and semistructured interviews, including contextual factors mentioned in these. A group-based exercise sought to identify and rank important generic contextual factors.RESULTS: A total of 79 candidate factors were listed. Across the 3 groups, gender/sex, comorbidities, and the healthcare system were ranked as most important.CONCLUSION: The identified important contextual factor domains may be considered a provisional list pending further research.

KW - Clinical trials

KW - Omeract

KW - Outcomes

KW - Rheumatic diseases

UR - https://www.scopus.com/pages/publications/85070395267

U2 - 10.3899/jrheum.181081

DO - 10.3899/jrheum.181081

M3 - Journal article

C2 - 30647174

SN - 0315-162X

VL - 46

SP - 1159

EP - 1163

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 9

ER -

Identifying Provisional Generic Contextual Factor Domains for Clinical Trials in Rheumatology: Results from an OMERACT Initiative

Abstract

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