Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

High-resolution nuclear magnetic resonance imaging and single photon emission computerized tomography--cerebral blood flow in a case of pure sensory stroke and mild dementia owing to subcortical arteriosclerotic encephalopathy (Binswanger's disease)

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Delayed reflow of an ischemic infarct after spontaneous thrombolysis studied by CBF tomography using SPECT and Tc-99m HMPAO

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Analyse af medicinske korttidsindlæggelser af ældre patienter med fokus på alternative løsninger

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Regulation of cerebral blood flow in patients with autonomic dysfunction and severe postural hypotension

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Vestibularis-schwannomers diagnostik og vaekst bedømt ved SPECT kombineret med TL-201 Thallium

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer
Pure sensory stroke (PSS) is typically caused by a lacunar infarct located in the ventral-posterior (VP) thalamic nucleus contralateral to the paresthetic symptoms. The lesion is usually so small that it cannot be seen on computerized tomography (CT), as illustrated by our case. In our moderately hypertensive, 72-year-old patient with PSS, CT scanning and conventional nuclear magnetic resonance imaging (NMRI) scanning using a 7-mm-thick slice on a 1.5 Tesla instrument all failed to visualize the thalamic infarct. Using the high-resolution mode with 2-mm slice thickness it was, however, clearly seen. In addition, NMRI unexpectedly showed diffuse periventricular demyelinization as well as three other lacunar infarcts, i.e., findings characteristic of subcortical arteriosclerotic encephalopathy (SAE). This prompted psychometric testing, which revealed signs of mild (subclinical) dementia, in particular involving visiospatial apraxia; this pointed to decreased function of the right parietal cortex, which was structurally intact on CT and NMRI. Single photon emission computerized tomography by Xenon-133 injection and by hexamethyl-propyleneamine-oxim labeled with Technetium-99m showed asymmetric distribution of cerebral blood flow (CBF), with an 18% lower value in the right parietal cortex compared to the left side; this indicated asymmetric disconnection of the cortex by the SAE. Thus, the tomograms of the functional parameter, CBF, correlated better with the deficits revealed by neuropsychological testing than by CT or NMRI.
OriginalsprogEngelsk
TidsskriftAmerican Journal of Physiologic Imaging
Vol/bind2
Udgave nummer4
Sider (fra-til)192-5
Antal sider4
ISSN0885-8276
StatusUdgivet - 1987

ID: 39048718