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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Hypokalemia and rhabdomyolysis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Vis graf over relationer

The adverse drug event manager of the Capital Region of Denmark received a report of a 65-year-old male with type II diabetes and long-lasting treatment with indapamide. In addition, he had a history of a high consumption of licorice. For 2 weeks, the patient suffered from myalgia, which the general practitioner suspected to be polymyalgia rheumatica and referred him to the hospital. Initial blood samples revealed a reduced potassium concentration of 1.5 mmol/L (reference value: 6.6-4.6 mmol/L) and an elevated creatine kinase of 18,400 IU/L (reference value: 40-280 IU/L). We believe that the patient developed rhabdomyolysis due to severe hypokalemia, possibly induced by a pharmacodynamic interaction between licorice and indapamide.

OriginalsprogEngelsk
TidsskriftJournal of pharmacology & pharmacotherapeutics
Vol/bind6
Udgave nummer2
Sider (fra-til)98-9
Antal sider2
ISSN0976-500X
DOI
StatusUdgivet - 15 maj 2015

ID: 66836156