Hypoglycemia in type 1 diabetic pregnancy: role of preconception insulin aspart treatment in a randomized study

Simon Heller; Peter Damm; Henriette Mersebach; Trine Vang Skjøth; Risto Kaaja; Moshe Hod; Santiago Durán-García; David McCance; Elisabeth R Mathiesen

doi:10.2337/dc09-1605

Hypoglycemia in type 1 diabetic pregnancy: role of preconception insulin aspart treatment in a randomized study

Simon Heller, Peter Damm, Henriette Mersebach, Trine Vang Skjøth, Risto Kaaja, Moshe Hod, Santiago Durán-García, David McCance, Elisabeth R Mathiesen

57 Citationer (Scopus)

Abstract

OBJECTIVE A recent randomized trial compared prandial insulin aspart (IAsp) with human insulin in type 1 diabetic pregnancy. The aim of this exploratory analysis was to investigate the incidence of severe hypoglycemia during pregnancy and compare women enrolled preconception with women enrolled during early pregnancy. RESEARCH DESIGN AND METHODS IAsp administered immediately before each meal was compared with human insulin administered 30 min before each meal in 99 subjects (44 to IAsp and 55 to human insulin) randomly assigned preconception and in 223 subjects (113 for IAsp and 110 for human insulin) randomly assigned in early pregnancy (

Originalsprog	Engelsk
Tidsskrift	Diabetes Care
Vol/bind	33
Udgave nummer	3
Sider (fra-til)	473-7
Antal sider	5
ISSN	0149-5992
DOI	https://doi.org/10.2337/dc09-1605
Status	Udgivet - 1 mar. 2010

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10.2337/dc09-1605

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abstract = "OBJECTIVE A recent randomized trial compared prandial insulin aspart (IAsp) with human insulin in type 1 diabetic pregnancy. The aim of this exploratory analysis was to investigate the incidence of severe hypoglycemia during pregnancy and compare women enrolled preconception with women enrolled during early pregnancy. RESEARCH DESIGN AND METHODS IAsp administered immediately before each meal was compared with human insulin administered 30 min before each meal in 99 subjects (44 to IAsp and 55 to human insulin) randomly assigned preconception and in 223 subjects (113 for IAsp and 110 for human insulin) randomly assigned in early pregnancy (",

author = "Simon Heller and Peter Damm and Henriette Mersebach and Skj{\o}th, {Trine Vang} and Risto Kaaja and Moshe Hod and Santiago Dur{\'a}n-Garc{\'i}a and David McCance and Mathiesen, {Elisabeth R}",

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T1 - Hypoglycemia in type 1 diabetic pregnancy: role of preconception insulin aspart treatment in a randomized study

AU - Heller, Simon

AU - Damm, Peter

AU - Mersebach, Henriette

AU - Skjøth, Trine Vang

AU - Kaaja, Risto

AU - Hod, Moshe

AU - Durán-García, Santiago

AU - McCance, David

AU - Mathiesen, Elisabeth R

PY - 2010/3/1

Y1 - 2010/3/1

N2 - OBJECTIVE A recent randomized trial compared prandial insulin aspart (IAsp) with human insulin in type 1 diabetic pregnancy. The aim of this exploratory analysis was to investigate the incidence of severe hypoglycemia during pregnancy and compare women enrolled preconception with women enrolled during early pregnancy. RESEARCH DESIGN AND METHODS IAsp administered immediately before each meal was compared with human insulin administered 30 min before each meal in 99 subjects (44 to IAsp and 55 to human insulin) randomly assigned preconception and in 223 subjects (113 for IAsp and 110 for human insulin) randomly assigned in early pregnancy (

AB - OBJECTIVE A recent randomized trial compared prandial insulin aspart (IAsp) with human insulin in type 1 diabetic pregnancy. The aim of this exploratory analysis was to investigate the incidence of severe hypoglycemia during pregnancy and compare women enrolled preconception with women enrolled during early pregnancy. RESEARCH DESIGN AND METHODS IAsp administered immediately before each meal was compared with human insulin administered 30 min before each meal in 99 subjects (44 to IAsp and 55 to human insulin) randomly assigned preconception and in 223 subjects (113 for IAsp and 110 for human insulin) randomly assigned in early pregnancy (

U2 - 10.2337/dc09-1605

DO - 10.2337/dc09-1605

M3 - Journal article

C2 - 20007944

SN - 0149-5992

VL - 33

SP - 473

EP - 477

JO - Diabetes Care

JF - Diabetes Care

IS - 3

ER -

Hypoglycemia in type 1 diabetic pregnancy: role of preconception insulin aspart treatment in a randomized study

Abstract

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