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Hypertensive nephropathy is associated with an increased risk of myeloma, skin, and renal cancer

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DOI

  1. Prognostic implications of left ventricular hypertrophy diagnosed on electrocardiogram vs echocardiography

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  2. Several Conventional Risk Markers Suggesting Presence of Albuminuria Are Weak Among Rural Africans With Hypertension

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  2. Quantification of cancer risk in glomerulonephritis

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Previous studies suggest an increased cancer risk in hypertension. Patients with hypertensive nephropathy have not been studied. A national registry study was performed to assess the presence and size of this association. Clinical data and cancer diagnoses for all patients with biopsy-proven hypertensive nephropathy between 1985 and 2015 in Denmark were extracted from four national registries and compared with age- and sex-adjusted national cancer rates. The risk of cancer was twice the background population. It was raised for renal cancer (odds ratio 10.4), myeloma (13.2), skin cancer (7.9), and other/unspecified (1.8). No increase in incidence was seen until 1 year before renal biopsy and then rose rapidly. It was again normal 5 years after biopsy. Hypertensive nephropathy is associated with an increased risk of myeloma, skin, renal, and other cancers. Screening of patients with hypertensive nephropathy, in the presence of reduced renal function or significant proteinuria, may be indicated.

OriginalsprogEngelsk
TidsskriftJournal of Clinical Hypertension
Vol/bind21
Udgave nummer6
Sider (fra-til)786-791
Antal sider6
ISSN1524-6175
DOI
StatusUdgivet - jun. 2019

Bibliografisk note

©2019 Wiley Periodicals, Inc.

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