Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study

Lars Peters; Jacqueline Neuhaus; Amanda Mocroft; Vincent Soriano; Jürgen Rockstroh; Gregory Dore; Massimo Puoti; Ellen Tedaldi; Bonaventura Clotet; Bernd Kupfer; Jens D Lundgren; Marina B Klein; SMART Study Group

doi:10.3851/IMP1815

Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study

Lars Peters, Jacqueline Neuhaus, Amanda Mocroft, Vincent Soriano, Jürgen Rockstroh, Gregory Dore, Massimo Puoti, Ellen Tedaldi, Bonaventura Clotet, Bernd Kupfer, Jens D Lundgren, Marina B Klein, SMART Study Group

15 Citationer (Scopus)

Abstract

In the SMART study, HIV-viral-hepatitis-coinfected persons were, compared with HIV-monoinfected persons, at higher risk of non-AIDS death if randomized to the antiretroviral therapy (ART) interruption strategy. We hypothesized that a marker of liver fibrosis, hyaluronic acid (HA), would be predictive of development of non-AIDS-related outcomes in coinfected participants in the SMART study.

Originalsprog	Engelsk
Tidsskrift	Antiviral Therapy
Vol/bind	16
Udgave nummer	5
Sider (fra-til)	667-75
Antal sider	9
ISSN	1359-6535
DOI	https://doi.org/10.3851/IMP1815
Status	Udgivet - 1 jan. 2011

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10.3851/IMP1815

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Peters, L., Neuhaus, J., Mocroft, A., Soriano, V., Rockstroh, J., Dore, G., Puoti, M., Tedaldi, E., Clotet, B., Kupfer, B., Lundgren, J. D., Klein, M. B., & SMART Study Group (2011). Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study. Antiviral Therapy, 16(5), 667-75. https://doi.org/10.3851/IMP1815

Peters, L, Neuhaus, J, Mocroft, A, Soriano, V, Rockstroh, J, Dore, G, Puoti, M, Tedaldi, E, Clotet, B, Kupfer, B, Lundgren, JD, Klein, MB & SMART Study Group 2011, 'Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study', Antiviral Therapy, bind 16, nr. 5, s. 667-75. https://doi.org/10.3851/IMP1815

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title = "Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study",

abstract = "In the SMART study, HIV-viral-hepatitis-coinfected persons were, compared with HIV-monoinfected persons, at higher risk of non-AIDS death if randomized to the antiretroviral therapy (ART) interruption strategy. We hypothesized that a marker of liver fibrosis, hyaluronic acid (HA), would be predictive of development of non-AIDS-related outcomes in coinfected participants in the SMART study.",

author = "Lars Peters and Jacqueline Neuhaus and Amanda Mocroft and Vincent Soriano and J{\"u}rgen Rockstroh and Gregory Dore and Massimo Puoti and Ellen Tedaldi and Bonaventura Clotet and Bernd Kupfer and Lundgren, {Jens D} and Klein, {Marina B} and {SMART Study Group}",

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AU - Peters, Lars

AU - Neuhaus, Jacqueline

AU - Mocroft, Amanda

AU - Soriano, Vincent

AU - Rockstroh, Jürgen

AU - Dore, Gregory

AU - Puoti, Massimo

AU - Tedaldi, Ellen

AU - Clotet, Bonaventura

AU - Kupfer, Bernd

AU - Lundgren, Jens D

AU - Klein, Marina B

AU - SMART Study Group

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AB - In the SMART study, HIV-viral-hepatitis-coinfected persons were, compared with HIV-monoinfected persons, at higher risk of non-AIDS death if randomized to the antiretroviral therapy (ART) interruption strategy. We hypothesized that a marker of liver fibrosis, hyaluronic acid (HA), would be predictive of development of non-AIDS-related outcomes in coinfected participants in the SMART study.

U2 - 10.3851/IMP1815

DO - 10.3851/IMP1815

M3 - Journal article

C2 - 21817188

SN - 1359-6535

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JO - Antiviral Therapy

JF - Antiviral Therapy

IS - 5

ER -

Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study

Abstract

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