Human infektionsimmunologi: Basalvidenskabelige opdagelser og kliniske konsekvenser

Michael Kemp*, Bente Klarlund Pedersen, Thor G. Theander

*Corresponding author af dette arbejde

Abstract

During the last years studies on human immune responses to specific micro-organisms have contributed to an increased understanding of the structure and function of the immune system. T lymphocytes with a special antigen receptor (gamma/delta cells) are thus probably important in some infectious diseases such as malaria and tuberculosis. The discovery of T-cell responses to protein-free fractions of mycobacteria and Leishmania parasites has lead to the identification of non-protein T-cell antigens. T-cells that express the CD4 receptor on their surface and are capable of lysing infected target cells have been found in viral infections. It has furthermore been found, that the composition of the signal mediators (cytokines) secreted by activated T-cells can determine the outcome of a number of infections. In the future it may be possible to include enhancement of protective immune reactions in the treatment of infectious diseases to a higher extent than now.

Bidragets oversatte titelHuman immunology of infection : Basal scientific findings and clinical consequences
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind162
Udgave nummer21
Sider (fra-til)3022-3023
Antal sider2
ISSN0041-5782
StatusUdgivet - 22 maj 2000
Udgivet eksterntJa

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