Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive inuencesof stray magnetic elds caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual dierences in MRCDI measurements for two dierent current proles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic elds show good agreement with in-vivo brain measurements.