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Udgivet

Home blood pressure in pregnancy-the upper reference limit

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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OBJECTIVES: To investigate whether the upper home blood pressure reference limit in healthy pregnant women correspond to 135/85 mmHg as used when diagnosing white coat hypertension outside pregnancy.

METHODS: In this prospective observational study 104 healthy, singleton pregnant women with a mean age of 32 ± 4 (±SD) years and with a median pre-pregnancy body mass index of 21 (interquartile range 20-24) kg/m were included. Home blood pressure was measured with the device Microlife® BP 3A Plus twice daily for three days (18 measurements in total) in addition to routine office blood pressure measurements in early (median 12+1 (weeks+days)), mid (20+0) and late pregnancy (35+3). Upper blood pressure reference limits were calculated as mean +2 SD.

RESULTS: Office blood pressure versus home blood pressure were 115 ± 11/72 ± 7 versus 103 ± 7/64 ± 5 mmHg in early pregnancy, 112 ± 11/74 ± 7 versus 102 ± 7/63 ± 5 mmHg in mid pregnancy and 118 ± 11/75 ± 8 versus 107 ± 8/66 ± 6 mmHg in late pregnancy. The mean difference between office blood pressure and home blood pressure was 10 mmHg. In late pregnancy, the upper reference limit was 140/91 mmHg for office blood pressure and 123/78 mmHg for home blood pressure with slightly lower values in early and mid pregnancy, respectively.

CONCLUSION: In late pregnancy, the upper home blood pressure reference limit in a population of healthy women was 123/78 mmHg. This value questions the generally proposed level of 135/85 mmHg to define white coat hypertension in pregnancy.

OriginalsprogEngelsk
TidsskriftBlood Pressure Monitoring
Vol/bind24
Udgave nummer4
Sider (fra-til)191-198
Antal sider8
ISSN1359-5237
DOI
StatusUdgivet - 1 aug. 2019

ID: 57290818