HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24

Lea Brandt; Thomas Benfield; Gitte Kronborg; Jan Gerstoft; Anders Fomsgaard; Ingrid Karlsson

doi:10.1097/QAI.0b013e31828fa22b

HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24

Lea Brandt
, Thomas Benfield
, Gitte Kronborg
, Jan Gerstoft
, Anders Fomsgaard
, Ingrid Karlsson

8 Citationer (Scopus)

Abstract

Still no effective HIV-1 prophylactic or therapeutic vaccines are available. However, as the proportion of HIV-1-infected individuals on antiretroviral treatment is increasing, knowledge about the residual immune response is important for the possible development of an HIV-1 vaccine.

Originalsprog	Engelsk
Tidsskrift	Journal of Acquired Immune Deficiency Syndromes (1999)
Vol/bind	63
Udgave nummer	4
Sider (fra-til)	418-27
Antal sider	10
ISSN	1525-4135
DOI	https://doi.org/10.1097/QAI.0b013e31828fa22b
Status	Udgivet - 1 aug. 2013

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10.1097/QAI.0b013e31828fa22b

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title = "HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24",

abstract = "Still no effective HIV-1 prophylactic or therapeutic vaccines are available. However, as the proportion of HIV-1-infected individuals on antiretroviral treatment is increasing, knowledge about the residual immune response is important for the possible development of an HIV-1 vaccine.",

keywords = "Antiretroviral Therapy, Highly Active, Antiviral Agents, CD4 Lymphocyte Count, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cells, Cultured, Cytokines, Female, HIV Core Protein p24, HIV Infections, HIV Integrase, HIV-1, HLA Antigens, Humans, Male, RNA, Viral, Viral Load, nef Gene Products, Human Immunodeficiency Virus",

author = "Lea Brandt and Thomas Benfield and Gitte Kronborg and Jan Gerstoft and Anders Fomsgaard and Ingrid Karlsson",

year = "2013",

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doi = "10.1097/QAI.0b013e31828fa22b",

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T1 - HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24

AU - Brandt, Lea

AU - Benfield, Thomas

AU - Kronborg, Gitte

AU - Gerstoft, Jan

AU - Fomsgaard, Anders

AU - Karlsson, Ingrid

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Still no effective HIV-1 prophylactic or therapeutic vaccines are available. However, as the proportion of HIV-1-infected individuals on antiretroviral treatment is increasing, knowledge about the residual immune response is important for the possible development of an HIV-1 vaccine.

AB - Still no effective HIV-1 prophylactic or therapeutic vaccines are available. However, as the proportion of HIV-1-infected individuals on antiretroviral treatment is increasing, knowledge about the residual immune response is important for the possible development of an HIV-1 vaccine.

KW - Antiretroviral Therapy, Highly Active

KW - Antiviral Agents

KW - CD4 Lymphocyte Count

KW - CD4-Positive T-Lymphocytes

KW - CD8-Positive T-Lymphocytes

KW - Cells, Cultured

KW - Cytokines

KW - Female

KW - HIV Core Protein p24

KW - HIV Infections

KW - HIV Integrase

KW - HIV-1

KW - HLA Antigens

KW - Humans

KW - Male

KW - RNA, Viral

KW - Viral Load

KW - nef Gene Products, Human Immunodeficiency Virus

U2 - 10.1097/QAI.0b013e31828fa22b

DO - 10.1097/QAI.0b013e31828fa22b

M3 - Journal article

C2 - 23507659

SN - 1525-4135

VL - 63

SP - 418

EP - 427

JO - Journal of Acquired Immune Deficiency Syndromes (1999)

JF - Journal of Acquired Immune Deficiency Syndromes (1999)

IS - 4

ER -

HIV-1-infected individuals in antiretroviral therapy react specifically with polyfunctional T-cell responses to Gag p24

Abstract

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