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E-pub ahead of print

High risk - what's next? A survey study on decisional conflict, regret and satisfaction among high-risk pregnant women making choices about further prenatal testing for fetal aneuploidy

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DOI

  1. Corrigendum for Hartwig TS, Sørensen S and Jørgensen FS (2016) https://doi.org/10.1002/pd.4833

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OBJECTIVES: To investigate decision-making among pregnant women when choosing between non-invasive prenatal testing, invasive testing or no further testing.

METHODS: Women with a high-risk result from the first trimester screening were invited to fill in two online questionnaires at gestational age 12-14(Q1) and 24(Q2). The scales used were Decisional Conflict and Regret Scales, Satisfaction with genetic Counselling Scale and Health-Relevant Personality Inventory.

RESULTS: 339 women agreed to participate, and the response rates were 76 % on Q1 and 88% on Q2. 75.4% chose an invasive test, 23.8% chose NIPT, 0.4% chose no further testing and 0.4% had both NIPT and invasive testing. Among all participants 13.3% had a high level of decisional conflict. We found that choosing NIPT was associated with a high decisional conflict (p=0.013); receiving genetic counselling the same day was associated with a high decisional conflict (p=0.039); and a high satisfaction with the genetic counselling was associated with low decisional conflict (p<0.001). Furthermore, the personality sub-trait 'alexithymia' was associated with low decisional conflict (p=0.043). There was a significant association between high decisional conflict and later decisional regret (p=0.008).

CONCLUSION: We present evidence, that satisfaction with and timing of counselling are important factors to limit decisional conflict. Interestingly, women choosing NIPT had more decisional conflict than women choosing invasive testing.

OriginalsprogEngelsk
TidsskriftPrenatal Diagnosis
ISSN0197-3851
DOI
StatusE-pub ahead of print - 13 maj 2019

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