High-resolution Regulatory Maps Connect Vascular Risk Variants to Disease Related Pathways

Keyphrases

• Risk Variant 100%
• Disease-related 100%
• Coronary Artery Disease 100%
• High-resolution 100%
• Vascular Risk 100%
• Related Pathway 100%
• Cardiovascular Disease 66%
• Genome-wide Association Study 66%
• Genetic Variants 66%
• Expression Level 66%
• Relevant Genes 66%
• Macrophages 33%
• Smooth muscle Cells 33%
• Lipopolysaccharide 33%
• Disease Risk 33%
• Strong Correlation 33%
• Transcriptome 33%
• Disease Variants 33%
• Cardiovascular Pathology 33%
• Chromatin Immunoprecipitation (ChIP) 33%
• THP1 33%
• Enhancer Element 33%
• Monocytic Cells 33%
• Non-coding Variants 33%
• H3K27ac 33%
• Genomic Interactions 33%
• Human Leukemia 33%
• High-throughput Chromosome Conformation Capture (Hi-C) 33%
• Interaction Map 33%
• Potential Target Genes 33%
• Dual Promoter 33%
• Sequence Capture 33%

Biochemistry, Genetics and Molecular Biology

• Enhancer Region 100%
• Genetic Divergence 50%
• Promoter Region 50%
• Genome-Wide Association Study 50%
• Candidate Gene 25%
• Haplotype 25%
• Macrophage 25%
• Transcriptome 25%
• Lipopolysaccharide 25%
• Chromatin Immunoprecipitation 25%