High resolution comparative genomic hybridisation analysis reveals imbalances in dyschromosomal patients with normal or apparently balanced conventional karyotypes

M Kirchhoff, H Rose, J Maahr, T Gerdes, M Bugge, N Tommerup, Z Tümer, J Lespinasse, P K Jensen, J Wirth, C Lundsteen

Abstrakt

A sensitive technique is needed for screening whole genome imbalances in dyschromosomal patients when G-banding shows normal karyotypes or apparently balanced translocations. In this study we performed highly sensitive comparative genomic hybridisation analysis on a number of such cases and revealed chromosomal imbalances in all.

OriginalsprogEngelsk
TidsskriftEuropean journal of human genetics : EJHG
Vol/bind8
Udgave nummer9
Sider (fra-til)661-8
Antal sider8
ISSN1018-4813
DOI
StatusUdgivet - sep. 2000
Udgivet eksterntJa

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