TY - JOUR
T1 - High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer
AU - Nielsen, H
AU - Daugaard, G
AU - Tvede, M
AU - Bruun, B
PY - 1992/10
Y1 - 1992/10
N2 - A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients.
AB - A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients.
KW - Antineoplastic Combined Chemotherapy Protocols/administration & dosage
KW - Bleomycin/administration & dosage
KW - Cisplatin/administration & dosage
KW - Clostridioides difficile/isolation & purification
KW - Diarrhea/drug therapy
KW - Etoposide/administration & dosage
KW - Humans
KW - Immunocompromised Host
KW - Neoplasms, Germ Cell and Embryonal/drug therapy
KW - Prevalence
KW - Prospective Studies
U2 - 10.1038/bjc.1992.334
DO - 10.1038/bjc.1992.334
M3 - Journal article
C2 - 1384640
SN - 0007-0920
VL - 66
SP - 666
EP - 667
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 4
ER -