High incidence of osteoporosis and cachexia in patients with newly diagnosed polymyalgia rheumatic and giant cell arteritis: 7th Asia-Pacific Osteoporosis Conference

Amir Emamifar, Anne Pernille Hermann, Torkell Juulsgaard Ellingsen, Søren Hess, Inger Marie Jensen Hansen, Peter Thye-Rønn

Abstract

Objectives: The objective of this cross-sectional analysis was to evaluate the incidence of osteoporosis and body composition aberrations in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) patients at time of diagnosis. Methods: This is an ongoing prospective study. 37 consecutive patients with newly diagnosed PMR/GCA were included. The patients were requested to perform a total body DXA at time of diagnosis or shortly after. Data from Swiss population of healthy adults (2986 men, 2649 women) were used to classify our patients according to body composition [1,2]. Results: Of 37 patients, 3 pts. were excluded from the study because of lack of interest or a change in the initial diagnosis. Statistical analyses were performed for the rest 34 pts. Results of DXA scan were available for 30 pts. Of all included pts. 61.8% were female and mean age (confidence interval) was 71 (69-74) y. At diagnosis, 24 pts. presented with pure PMR symptoms, 2 pts. with pure cranial GCA, 8 pts. with concurrent PMR and GCA. Results of body composition assessed by DXA scan are summarized in Table 1. 23.3% of patients had low muscle mass (underlean, FFMI90th percentile). 20% of the patients were categorized to have cachexia (FFMI25) and 3.3% (FFMI
OriginalsprogEngelsk
Publikationsdato2018
StatusUdgivet - 2018
Udgivet eksterntJa

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