High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Fysik og astronomi

• genome 78%
• genes 70%
• cancer 56%
• sequencing 32%
• gene expression 32%
• oncogenes 21%
• methylation 19%
• stomach 17%
• kidneys 15%
• liver 13%
• deactivation 13%
• proximity 11%
• deoxyribonucleic acid 10%

Medicin og biovidenskab

• Gene Rearrangement 70%
• Genome 40%
• Kidney Neoplasms 33%
• Genes 24%
• Neoplasms 19%
• Genetic Enhancer Elements 19%
• Gene Expression 18%
• Whole Genome Sequencing 17%
• RNA Sequence Analysis 16%
• Neoplasm Genes 16%
• DNA Methylation 14%
• Sarcoma 14%
• Stomach Neoplasms 13%
• Melanoma 12%
• Up-Regulation 10%
• Liver 7%

Kemi

• RNA Sequencing 100%
• Enhancer 71%