Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study

Katrine K Hedengran; Dick Nelson; Malene R Andersen; Steen Stender; Pal B Szecsi

doi:10.3109/14767058.2015.1052396

Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study

Katrine K Hedengran, Dick Nelson, Malene R Andersen, Steen Stender, Pal B Szecsi

Klinisk Biokemisk afd.

16 Citationer (Scopus)

Abstract

OBJECTIVE: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.

METHODS: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.

RESULTS: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.

CONCLUSION: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.

Originalsprog	Engelsk
Tidsskrift	The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Sider (fra-til)	1-3
Antal sider	3
ISSN	1476-7058
DOI	https://doi.org/10.3109/14767058.2015.1052396
Status	Udgivet - 29 jul. 2015

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10.3109/14767058.2015.1052396

Citationsformater

Hedengran, K. K., Nelson, D., Andersen, M. R., Stender, S., & Szecsi, P. B. (2015). Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 1-3. https://doi.org/10.3109/14767058.2015.1052396

Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study. / Hedengran, Katrine K; Nelson, Dick; Andersen, Malene R et al.
I: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 29.07.2015, s. 1-3.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Hedengran, KK, Nelson, D, Andersen, MR, Stender, S & Szecsi, PB 2015, 'Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study', The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, s. 1-3. https://doi.org/10.3109/14767058.2015.1052396

Hedengran KK, Nelson D, Andersen MR, Stender S, Szecsi PB. Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2015 jul. 29;1-3. doi: 10.3109/14767058.2015.1052396

Hedengran, Katrine K ; Nelson, Dick ; Andersen, Malene R et al. / Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study. I: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2015 ; s. 1-3.

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abstract = "OBJECTIVE: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.METHODS: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.RESULTS: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.CONCLUSION: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.",

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AU - Szecsi, Pal B

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N2 - OBJECTIVE: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.METHODS: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.RESULTS: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.CONCLUSION: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.

AB - OBJECTIVE: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.METHODS: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.RESULTS: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.CONCLUSION: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.

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Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - a prospective cohort study

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