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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Hepatitis B surface antigen quantity positively correlates with plasma levels of microRNAs differentially expressed in immunological phases of chronic hepatitis B in children

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Vis graf over relationer
Children with chronic hepatitis B (CHB) are at high risk of progressive liver disease. It is suggested that a newly-identified panel of 16 microRNAs is important in the pathogenesis of CHB in children. Subviral hepatitis B surface antigen (HBsAg) particles are produced in large excess over infectious virions. Interestingly, circulating HBsAg particles have been shown to carry microRNAs. A thorough characterisation of the identified microRNAs and HBsAg over time in plasma from children with CHB may provide useful information about the natural course of childhood CHB.
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind8
Udgave nummer11
Sider (fra-til)e80384
ISSN1932-6203
DOI
StatusUdgivet - 2013

ID: 43119845