Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals

Mette Bentz; Johanne Guldberg; Signe Vangkilde; Tine Pedersen; Kerstin Jessica Plessen; Jens Richardt Moellegaard Jepsen

doi:10.1371/journal.pone.0169183

Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals

Mette Bentz, Johanne Guldberg, Signe Vangkilde, Tine Pedersen, Kerstin Jessica Plessen, Jens Richardt Moellegaard Jepsen

20 Citationer (Scopus)

Abstract

INTRODUCTION: Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive.

OBJECTIVE: Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN.

METHODS: We used the Sniffin' Sticks Odor Threshold Test and Odor Identification Test to assess 43 participants with first-episode AN, 27 recovered participants, and 39 control participants. Participants completed the Importance of Olfaction questionnaire, the Beck Youth Inventory and the Eating Disorder Inventory. We also conducted a psychiatric diagnostic interview and the Autism Diagnostic Observation Schedule with participants.

RESULTS: Both clinical groups showed heightened olfactory sensitivity. After excluding participants with depression, participants with first-episode AN identified more odors than recovered participants.

CONCLUSION: Heightened olfactory sensitivity in AN may be independent of clinical status, whereas only individuals with current AN and without depression show more accurate odor identification.

Originalsprog	Engelsk
Artikelnummer	e0169183
Tidsskrift	P L o S One
Vol/bind	12
Udgave nummer	1
Sider (fra-til)	1-17
Antal sider	17
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0169183
Status	Udgivet - 6 jan. 2017

Adgang til dokumentet

10.1371/journal.pone.0169183

Citationsformater

@article{d798793498ef43929f8b3354cb60b03f,

title = "Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals",

abstract = "INTRODUCTION: Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive.OBJECTIVE: Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN.METHODS: We used the Sniffin' Sticks Odor Threshold Test and Odor Identification Test to assess 43 participants with first-episode AN, 27 recovered participants, and 39 control participants. Participants completed the Importance of Olfaction questionnaire, the Beck Youth Inventory and the Eating Disorder Inventory. We also conducted a psychiatric diagnostic interview and the Autism Diagnostic Observation Schedule with participants.RESULTS: Both clinical groups showed heightened olfactory sensitivity. After excluding participants with depression, participants with first-episode AN identified more odors than recovered participants.CONCLUSION: Heightened olfactory sensitivity in AN may be independent of clinical status, whereas only individuals with current AN and without depression show more accurate odor identification.",

author = "Mette Bentz and Johanne Guldberg and Signe Vangkilde and Tine Pedersen and Plessen, {Kerstin Jessica} and Jepsen, {Jens Richardt Moellegaard}",

year = "2017",

month = jan,

day = "6",

doi = "10.1371/journal.pone.0169183",

language = "English",

volume = "12",

pages = "1--17",

journal = "P L o S One",

issn = "1932-6203",

publisher = "Public Library of Science",

number = "1",

}

TY - JOUR

T1 - Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals

AU - Bentz, Mette

AU - Guldberg, Johanne

AU - Vangkilde, Signe

AU - Pedersen, Tine

AU - Plessen, Kerstin Jessica

AU - Jepsen, Jens Richardt Moellegaard

PY - 2017/1/6

Y1 - 2017/1/6

N2 - INTRODUCTION: Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive.OBJECTIVE: Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN.METHODS: We used the Sniffin' Sticks Odor Threshold Test and Odor Identification Test to assess 43 participants with first-episode AN, 27 recovered participants, and 39 control participants. Participants completed the Importance of Olfaction questionnaire, the Beck Youth Inventory and the Eating Disorder Inventory. We also conducted a psychiatric diagnostic interview and the Autism Diagnostic Observation Schedule with participants.RESULTS: Both clinical groups showed heightened olfactory sensitivity. After excluding participants with depression, participants with first-episode AN identified more odors than recovered participants.CONCLUSION: Heightened olfactory sensitivity in AN may be independent of clinical status, whereas only individuals with current AN and without depression show more accurate odor identification.

AB - INTRODUCTION: Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive.OBJECTIVE: Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN.METHODS: We used the Sniffin' Sticks Odor Threshold Test and Odor Identification Test to assess 43 participants with first-episode AN, 27 recovered participants, and 39 control participants. Participants completed the Importance of Olfaction questionnaire, the Beck Youth Inventory and the Eating Disorder Inventory. We also conducted a psychiatric diagnostic interview and the Autism Diagnostic Observation Schedule with participants.RESULTS: Both clinical groups showed heightened olfactory sensitivity. After excluding participants with depression, participants with first-episode AN identified more odors than recovered participants.CONCLUSION: Heightened olfactory sensitivity in AN may be independent of clinical status, whereas only individuals with current AN and without depression show more accurate odor identification.

U2 - 10.1371/journal.pone.0169183

DO - 10.1371/journal.pone.0169183

M3 - Journal article

C2 - 28060877

SN - 1932-6203

VL - 12

SP - 1

EP - 17

JO - P L o S One

JF - P L o S One

IS - 1

M1 - e0169183

ER -

Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater