TY - JOUR
T1 - Heart failure related cardiogenic shock
T2 - An ISHLT consensus conference content summary
AU - Kanwar, Manreet K
AU - Billia, Filio
AU - Randhawa, Varinder
AU - Cowger, Jennifer A
AU - Barnett, Christopher M
AU - Chih, Sharon
AU - Ensminger, Stephan
AU - Hernandez-Montfort, Jaime
AU - Sinha, Shashank S
AU - Vorovich, Esther
AU - Proudfoot, Alastair
AU - Lim, Hoong S
AU - Blumer, Vanessa
AU - Jennings, Douglas L
AU - Reshad Garan, A
AU - Renedo, Maria F
AU - Hanff, Thomas C
AU - Baran, David A
AU - Consensus Conference participants
A2 - Gustafsson, Finn
N1 - Copyright © 2023 International Society for the Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.
PY - 2024
Y1 - 2024
N2 - In recent years, there have been significant advancements in the understanding, risk-stratification, and treatment of cardiogenic shock (CS). Despite improved pharmacologic and device-based therapies for CS, short-term mortality remains as high as 50%. Most recent efforts in research have focused on CS related to acute myocardial infarction, even though heart failure related CS (HF-CS) accounts for >50% of CS cases. There is a paucity of high-quality evidence to support standardized clinical practices in approach to HF-CS. In addition, there is an unmet need to identify disease-specific diagnostic and risk-stratification strategies upon admission, which might ultimately guide the choice of therapies, and thereby improve outcomes and optimize resource allocation. The heterogeneity in defining CS, patient phenotypes, treatment goals and therapies has resulted in difficulty comparing published reports and standardized treatment algorithms. An International Society for Heart and Lung Transplantation (ISHLT) consensus conference was organized to better define, diagnose, and manage HF-CS. There were 54 participants (advanced heart failure and interventional cardiologists, cardiothoracic surgeons, critical care cardiologists, intensivists, pharmacists, and allied health professionals), with vast clinical and published experience in CS, representing 42 centers worldwide. State-of-the-art HF-CS presentations occurred with subsequent breakout sessions planned in an attempt to reach consensus on various issues, including but not limited to models of CS care delivery, patient presentations in HF-CS, and strategies in HF-CS management. This consensus report summarizes the contemporary literature review on HF-CS presented in the first half of the conference (part 1), while the accompanying document (part 2) covers the breakout sessions where the previously agreed upon clinical issues were discussed with an aim to get to a consensus.
AB - In recent years, there have been significant advancements in the understanding, risk-stratification, and treatment of cardiogenic shock (CS). Despite improved pharmacologic and device-based therapies for CS, short-term mortality remains as high as 50%. Most recent efforts in research have focused on CS related to acute myocardial infarction, even though heart failure related CS (HF-CS) accounts for >50% of CS cases. There is a paucity of high-quality evidence to support standardized clinical practices in approach to HF-CS. In addition, there is an unmet need to identify disease-specific diagnostic and risk-stratification strategies upon admission, which might ultimately guide the choice of therapies, and thereby improve outcomes and optimize resource allocation. The heterogeneity in defining CS, patient phenotypes, treatment goals and therapies has resulted in difficulty comparing published reports and standardized treatment algorithms. An International Society for Heart and Lung Transplantation (ISHLT) consensus conference was organized to better define, diagnose, and manage HF-CS. There were 54 participants (advanced heart failure and interventional cardiologists, cardiothoracic surgeons, critical care cardiologists, intensivists, pharmacists, and allied health professionals), with vast clinical and published experience in CS, representing 42 centers worldwide. State-of-the-art HF-CS presentations occurred with subsequent breakout sessions planned in an attempt to reach consensus on various issues, including but not limited to models of CS care delivery, patient presentations in HF-CS, and strategies in HF-CS management. This consensus report summarizes the contemporary literature review on HF-CS presented in the first half of the conference (part 1), while the accompanying document (part 2) covers the breakout sessions where the previously agreed upon clinical issues were discussed with an aim to get to a consensus.
KW - Heart Failure/complications
KW - Humans
KW - Myocardial Infarction
KW - Shock, Cardiogenic/diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85182223141&partnerID=8YFLogxK
U2 - 10.1016/j.healun.2023.09.014
DO - 10.1016/j.healun.2023.09.014
M3 - Journal article
C2 - 38069920
SN - 1053-2498
VL - 43
SP - 189
EP - 203
JO - The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
JF - The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
IS - 2
ER -