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Hashimoto's encephalopathy: A rare proteiform disorder

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Harvard

Montagna, G, Imperiali, M, Agazzi, P, D'Aurizio, F, Tozzoli, R, Feldt-Rasmussen, U & Giovanella, L 2016, 'Hashimoto's encephalopathy: A rare proteiform disorder' Journal of Autoimmunity, bind 15, nr. 5, s. 466-76. https://doi.org/10.1016/j.autrev.2016.01.014

APA

Montagna, G., Imperiali, M., Agazzi, P., D'Aurizio, F., Tozzoli, R., Feldt-Rasmussen, U., & Giovanella, L. (2016). Hashimoto's encephalopathy: A rare proteiform disorder. Journal of Autoimmunity, 15(5), 466-76. https://doi.org/10.1016/j.autrev.2016.01.014

CBE

Montagna G, Imperiali M, Agazzi P, D'Aurizio F, Tozzoli R, Feldt-Rasmussen U, Giovanella L. 2016. Hashimoto's encephalopathy: A rare proteiform disorder. Journal of Autoimmunity. 15(5):466-76. https://doi.org/10.1016/j.autrev.2016.01.014

MLA

Vancouver

Author

Montagna, Giacomo ; Imperiali, Mauro ; Agazzi, Pamela ; D'Aurizio, Federica ; Tozzoli, Renato ; Feldt-Rasmussen, Ulla ; Giovanella, Luca. / Hashimoto's encephalopathy : A rare proteiform disorder. I: Journal of Autoimmunity. 2016 ; Bind 15, Nr. 5. s. 466-76.

Bibtex

@article{a04895fcbe4145a8bb8319d9de5a1049,
title = "Hashimoto's encephalopathy: A rare proteiform disorder",
abstract = "Hashimoto's encephalopathy (HE) is a rare not well understood, progressive and relapsing multiform disease, characterized by seizures, movement disorders, subacute cognitive dysfunction, psychiatric symptoms and responsiveness to steroid therapy. The disorder is generally associated with thyroid diseases and the most common feature is the presence of anti-thyroperoxidase antibodies (TPOAb). Patients are usually euthyroid or mildly hypothyroid at presentation. All age groups can be affected. The pathophysiology is still unclear, especially the link between elevated serum TPOAb and the encephalopathy. Most reported cases occurred in women and girls. Unspecific symptoms, non-pathognomonic laboratory neurophysiology and neuroimaging features make its diagnosis a real challenge for clinicians. The case of a 16 year old boy, with a clinical picture of HE associated with hypothyroidism, demonstrating an excellent response to high dose steroids is presented together with a systematic review of the literature.",
keywords = "Autoantigens, Biomarkers, Cognition Disorders, Diagnosis, Differential, Encephalitis, Hashimoto Disease, Humans, Iodide Peroxidase, Iron-Binding Proteins, Steroids, Treatment Outcome, Journal Article, Review",
author = "Giacomo Montagna and Mauro Imperiali and Pamela Agazzi and Federica D'Aurizio and Renato Tozzoli and Ulla Feldt-Rasmussen and Luca Giovanella",
note = "Copyright {\circledC} 2016 Elsevier B.V. All rights reserved.",
year = "2016",
month = "5",
doi = "10.1016/j.autrev.2016.01.014",
language = "English",
volume = "15",
pages = "466--76",
journal = "Journal of Autoimmunity",
issn = "0896-8411",
publisher = "Academic Press",
number = "5",

}

RIS

TY - JOUR

T1 - Hashimoto's encephalopathy

T2 - A rare proteiform disorder

AU - Montagna, Giacomo

AU - Imperiali, Mauro

AU - Agazzi, Pamela

AU - D'Aurizio, Federica

AU - Tozzoli, Renato

AU - Feldt-Rasmussen, Ulla

AU - Giovanella, Luca

N1 - Copyright © 2016 Elsevier B.V. All rights reserved.

PY - 2016/5

Y1 - 2016/5

N2 - Hashimoto's encephalopathy (HE) is a rare not well understood, progressive and relapsing multiform disease, characterized by seizures, movement disorders, subacute cognitive dysfunction, psychiatric symptoms and responsiveness to steroid therapy. The disorder is generally associated with thyroid diseases and the most common feature is the presence of anti-thyroperoxidase antibodies (TPOAb). Patients are usually euthyroid or mildly hypothyroid at presentation. All age groups can be affected. The pathophysiology is still unclear, especially the link between elevated serum TPOAb and the encephalopathy. Most reported cases occurred in women and girls. Unspecific symptoms, non-pathognomonic laboratory neurophysiology and neuroimaging features make its diagnosis a real challenge for clinicians. The case of a 16 year old boy, with a clinical picture of HE associated with hypothyroidism, demonstrating an excellent response to high dose steroids is presented together with a systematic review of the literature.

AB - Hashimoto's encephalopathy (HE) is a rare not well understood, progressive and relapsing multiform disease, characterized by seizures, movement disorders, subacute cognitive dysfunction, psychiatric symptoms and responsiveness to steroid therapy. The disorder is generally associated with thyroid diseases and the most common feature is the presence of anti-thyroperoxidase antibodies (TPOAb). Patients are usually euthyroid or mildly hypothyroid at presentation. All age groups can be affected. The pathophysiology is still unclear, especially the link between elevated serum TPOAb and the encephalopathy. Most reported cases occurred in women and girls. Unspecific symptoms, non-pathognomonic laboratory neurophysiology and neuroimaging features make its diagnosis a real challenge for clinicians. The case of a 16 year old boy, with a clinical picture of HE associated with hypothyroidism, demonstrating an excellent response to high dose steroids is presented together with a systematic review of the literature.

KW - Autoantigens

KW - Biomarkers

KW - Cognition Disorders

KW - Diagnosis, Differential

KW - Encephalitis

KW - Hashimoto Disease

KW - Humans

KW - Iodide Peroxidase

KW - Iron-Binding Proteins

KW - Steroids

KW - Treatment Outcome

KW - Journal Article

KW - Review

U2 - 10.1016/j.autrev.2016.01.014

DO - 10.1016/j.autrev.2016.01.014

M3 - Journal article

VL - 15

SP - 466

EP - 476

JO - Journal of Autoimmunity

JF - Journal of Autoimmunity

SN - 0896-8411

IS - 5

ER -

ID: 49765425