Hand-related physical function in rheumatic hand conditions: a protocol for developing a patient-reported outcome measurement instrument

Louise Klokker, Caroline B Terwee, Eva Ejlersen Wæhrens, Marius Henriksen, Sandra Nolte, Gregor Liegl, Margreet Kloppenburg, Rene Westhoven, Ruth Wittoek, Ingvild Kjeken, Ida K Haugen, Ben Schalet, Richard Gershon, Henning Bliddal, Robin Christensen

2 Citationer (Scopus)

Abstract

INTRODUCTION: There is no consensus about what constitutes the most appropriate patient-reported outcome measurement (PROM) instrument for measuring physical function in patients with rheumatic hand conditions. Existing instruments lack psychometric testing and vary in feasibility and their psychometric qualities. We aim to develop a PROM instrument to assess hand-related physical function in rheumatic hand conditions.

METHODS AND ANALYSIS: We will perform a systematic search to identify existing PROMs to rheumatic hand conditions, and select items relevant for hand-related physical function as well as those items from the Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) item bank that are relevant to patients with rheumatic hand conditions. Selection will be based on consensus among reviewers. Content validity of selected items will be established through the use of focus groups. If patients deem necessary, we will develop new items based on the patients' input. We will examine whether it is valid to score all selected and developed items on the same scale as the original items from the PROMIS PF item bank. Our analyses will follow the methods used for calibrating the original PROMIS PF item bank in US samples, which were largely based on the general PROMIS approach.

ETHICS AND DISSEMINATION: This study will be carried out in accordance with the Helsinki Declaration. Ethics approvals will be obtained where necessary, and signed informed consent will be obtained from all participants. We aim to disseminate the results of the study through publication in international peer-reviewed journals and at international conferences.

OriginalsprogEngelsk
TidsskriftB M J Open
Vol/bind6
Udgave nummer12
Sider (fra-til)e011174
ISSN2044-6055
DOI
StatusUdgivet - 14 dec. 2016

Fingeraftryk

Dyk ned i forskningsemnerne om 'Hand-related physical function in rheumatic hand conditions: a protocol for developing a patient-reported outcome measurement instrument'. Sammen danner de et unikt fingeraftryk.

Citationsformater