Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital

Hand exercise for women with rheumatoid arthritis and decreased hand function: an exploratory randomized controlled trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review


  1. The immune system in sporadic inclusion body myositis patients is not compromised by blood-flow restricted exercise training

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Very early MRI responses to therapy as a predictor of later radiographic progression in early rheumatoid arthritis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. The need for comparative data in spondyloarthritis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: People with hand-related rheumatoid arthritis (RA) experience problems performing activities of daily living (ADL). Compensatory strategies to improve ADL ability have shown effective. Similarly, hand exercise has shown effect on pain, grip strength, and self-reported ability. A combination has shown positive effects based on self-report, but self-report and observation provide distinct information about ADL. The purpose of this study was to examine whether hand exercise as add on to compensatory intervention (CIP) will improve observed ADL ability in RA.

METHODS: Women (n = 55) with hand-related RA were randomized to CIPEXERCISE (intervention) or CIP only (control). CIP is focused on joint protection, assistive devices, and alternative ways of performing AD. The hand-exercise program addressed range of motion and muscle strength. Primary outcome was change in observed ADL motor ability measured by the Assessment of Motor and Process Skills (AMPS). Baseline measures were repeated after 8 weeks.

RESULTS: Improvements in ADL motor ability in CIPEXERCISE (mean change = 0.24 logits; 95% CI = 0.09 to 0.39) and CIPCONTROL (mean change =0.20 logits; 95% CI = 0.05 to 0.35) were statistically significant, with no differences between groups (mean difference = 0.04 logits; 95% CI = - 0.16 to 0.25). Thirteen (46.4%) participants in the CIPEXERCISE and 12 (44.4%) in the CIPCONTROL obtained clinically relevant improvements (≥ 0.30 logits) in ADL motor ability; this group difference was not significant (z = 0.15; p = 0.88).

CONCLUSION: Adding hand exercise to a compensatory intervention did not yield additional benefits in women with hand-related RA. The study was approved by the ethics committee 14th of April 2014 (H-3-2014-025) and registered at 16th of May 2014 (NCT02140866).

TidsskriftArthritis Research & Therapy
Udgave nummer1
Sider (fra-til)158
StatusUdgivet - 26 jun. 2019

ID: 57522501