TY - JOUR
T1 - Guidelines for the correct use of the nomenclature of biochemical indices of bone status
T2 - a position statement of the Joint IOF Working Group and IFCC Committee on Bone Metabolism
AU - Lombardi, Giovanni
AU - Jørgensen, Niklas Rye
AU - Harvey, Nicholas C
AU - McCloskey, Eugene V
AU - Åkesson, Kristina E
AU - Eastell, Richard
AU - Garnero, Patrick
AU - Kanis, John A
AU - Khashayar, Patricia
AU - Lane, Nancy E
AU - McClung, Michael R
AU - Silverman, Stuart
AU - Makris, Konstantinos
AU - Bhattoa, Harjit Pal
AU - Vasikaran, Samuel D
AU - Pikner, Richard
AU - Cavalier, Etienne
AU - Joint IOF Working Group and IFCC Committee on Bone Metabolism
N1 - © 2024 Walter de Gruyter GmbH, Berlin/Boston.
PY - 2025/3/26
Y1 - 2025/3/26
N2 - The presented guidelines are an update of the position paper, endorsed by the International Osteoporosis Foundation (IOF), on nomenclature of bone markers published over 2 decades ago. Novel insight into bone biology and pathophysiology of bone disorders has highlighted the increasing relevance of new and known mediators implicated in various aspects of bone metabolism. This updated guideline proposes the nomenclature Bone Status Indices (BSI) as the comprehensive classification rather than bone turnover markers, bone markers, metabolic markers of bone turnover or metabolic markers of bone turnover, that are currently in use for the implicated molecules. On behalf of the IFCC Committee on Bone Metabolism and the Joint IOF Working Group and IFCC Committee on Bone Metabolism, the authors propose standardized nomenclature, abbreviations and measurement units for the bone status indices.
AB - The presented guidelines are an update of the position paper, endorsed by the International Osteoporosis Foundation (IOF), on nomenclature of bone markers published over 2 decades ago. Novel insight into bone biology and pathophysiology of bone disorders has highlighted the increasing relevance of new and known mediators implicated in various aspects of bone metabolism. This updated guideline proposes the nomenclature Bone Status Indices (BSI) as the comprehensive classification rather than bone turnover markers, bone markers, metabolic markers of bone turnover or metabolic markers of bone turnover, that are currently in use for the implicated molecules. On behalf of the IFCC Committee on Bone Metabolism and the Joint IOF Working Group and IFCC Committee on Bone Metabolism, the authors propose standardized nomenclature, abbreviations and measurement units for the bone status indices.
KW - Biomarkers/metabolism
KW - Bone and Bones/metabolism
KW - Humans
KW - Osteoporosis/diagnosis
KW - Terminology as Topic
UR - http://www.scopus.com/inward/record.url?scp=85210923661&partnerID=8YFLogxK
U2 - 10.1515/cclm-2024-1148
DO - 10.1515/cclm-2024-1148
M3 - Journal article
C2 - 39576737
SN - 1434-6621
VL - 63
SP - 704
EP - 711
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
IS - 4
ER -