Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

Ida Nikoline Mandic; Victoria Elizabeth de Knegt; Hristo Stanchev; Tine Brink Henriksen; Emma Louise Malchau Carlsen; Maren Johanne Heilskov Rytter

doi:10.61409/V01240022

Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

Ida Nikoline Mandic, Victoria Elizabeth de Knegt, Hristo Stanchev, Tine Brink Henriksen, Emma Louise Malchau Carlsen, Maren Johanne Heilskov Rytter

Afdeling for Intensiv behandling af nyfødte og mindre børn

1 Citationer (Scopus)

Abstract

Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

Bidragets oversatte titel	Group B streptococci in newborns in the first three months of life
Originalsprog	Dansk
Artikelnummer	V01240022
Tidsskrift	Ugeskrift for Laeger
Vol/bind	186
Udgave nummer	26
ISSN	0041-5782
DOI	https://doi.org/10.61409/V01240022
Status	Udgivet - 24 jun. 2024

Emneord

Humans
Streptococcal Infections/diagnosis
Infant, Newborn
Streptococcus agalactiae/isolation & purification
Anti-Bacterial Agents/therapeutic use
Female
Pregnancy
Denmark/epidemiology
Pregnancy Complications, Infectious/diagnosis
Infant
Streptococcal Vaccines/administration & dosage
Infectious Disease Transmission, Vertical/prevention & control

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10.61409/V01240022Licens: CC BY-NC-ND

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https://ugeskriftet.dk/videnskab/gruppe-b-streptokokker-hos-nyfoedte-og-i-de-foerste-tre-levemaaneder

Citationsformater

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abstract = "Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.",

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author = "Mandic, {Ida Nikoline} and {de Knegt}, {Victoria Elizabeth} and Hristo Stanchev and Henriksen, {Tine Brink} and Carlsen, {Emma Louise Malchau} and Rytter, {Maren Johanne Heilskov}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2024",

month = jun,

day = "24",

doi = "10.61409/V01240022",

language = "Dansk",

volume = "186",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

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TY - JOUR

T1 - Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

AU - Mandic, Ida Nikoline

AU - de Knegt, Victoria Elizabeth

AU - Stanchev, Hristo

AU - Henriksen, Tine Brink

AU - Carlsen, Emma Louise Malchau

AU - Rytter, Maren Johanne Heilskov

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024/6/24

Y1 - 2024/6/24

N2 - Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

AB - Group B Streptococcus (GBS) disease in neonates occurs in two forms: early-onset disease (EOD), (day 0-6), and late-onset disease (LOD), (day 7-90). This review investigates that risk-based intrapartum screening and antibiotics have reduced the incidence of EOD, but not LOD, in Denmark. No clinical or laboratory tests can rule out GBS disease at symptom onset. Thus, a high proportion of uninfected infants receive antibiotics, although this varies widely, and may be reduced by strategies of antibiotic stewardship. A future GBS vaccine for pregnant women may potentially reduce disease burden and antibiotic exposure.

KW - Humans

KW - Streptococcal Infections/diagnosis

KW - Infant, Newborn

KW - Streptococcus agalactiae/isolation & purification

KW - Anti-Bacterial Agents/therapeutic use

KW - Female

KW - Pregnancy

KW - Denmark/epidemiology

KW - Pregnancy Complications, Infectious/diagnosis

KW - Infant

KW - Streptococcal Vaccines/administration & dosage

KW - Infectious Disease Transmission, Vertical/prevention & control

UR - https://ugeskriftet.dk/videnskab/gruppe-b-streptokokker-hos-nyfoedte-og-i-de-foerste-tre-levemaaneder

U2 - 10.61409/V01240022

DO - 10.61409/V01240022

M3 - Review

C2 - 38953689

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 26

M1 - V01240022

ER -

Gruppe B-streptokokker hos nyfødte og i de første tre levemåneder

Abstract

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