Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Growth and differentiation factor 15 as a biomarker for mitochondrial myopathy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Muscle contractility of leg muscles in patients with mitochondrial myopathies

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Mitochondrial dysfunction underlying outer retinal diseases

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. Impaired lipolysis in propionic acidemia: A new metabolic myopathy?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Absence of p.R50X Pygm read-through in McArdle disease cellular models

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. European muscle MRI study in limb girdle muscular dystrophy type R1/2A (LGMDR1/LGMD2A)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVE: We investigated if Growth and Differentiation Factor 15 (GDF-15) can be used as a biomarker to distinguish patients with mitochondrial myopathy from patients with other myopathies.

METHODS: Serum GDF-15 was measured in 28 patients with mitochondrial disease, 24 with metabolic myopathies, 27 with muscular dystrophy and 21 healthy controls.

RESULTS AND CONCLUSIONS: Our findings indicate that elevated GDF-15 can distinguish patients with mitochondrial myopathy from other myopathies, including metabolic myopathies. This suggests that increases in GDF-15 is specific to respiratory chain dysfunction rather than general metabolic dysfunction or muscle defect.

OriginalsprogEngelsk
TidsskriftMitochondrion
Vol/bind50
Sider (fra-til)35-41
Antal sider7
ISSN1567-7249
DOI
StatusUdgivet - jan. 2020

Bibliografisk note

Copyright © 2019 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

ID: 58350438