Glutathione Preservation during Storage of Rat Lenses in Optisol-GS and Castor Oil

Thomas  Holm; Martin Rocho Brøgger-Jensen; Leif Johnson; Line Kessel

doi:10.1371/journal.pone.0079620

Glutathione Preservation during Storage of Rat Lenses in Optisol-GS and Castor Oil

Thomas Holm, Martin Rocho Brøgger-Jensen, Leif Johnson, Line Kessel

Afdeling for Øjensygdomme

5 Citationer (Scopus)

Abstract

Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens condition, determined from their ability to maintain glutathione concentrations.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	8
Udgave nummer	11
Sider (fra-til)	e79620
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0079620
Status	Udgivet - 2013

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10.1371/journal.pone.0079620

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title = "Glutathione Preservation during Storage of Rat Lenses in Optisol-GS and Castor Oil",

abstract = "Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens condition, determined from their ability to maintain glutathione concentrations.",

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AU - Holm, Thomas

AU - Brøgger-Jensen, Martin Rocho

AU - Johnson, Leif

AU - Kessel, Line

PY - 2013

Y1 - 2013

N2 - Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens condition, determined from their ability to maintain glutathione concentrations.

AB - Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens condition, determined from their ability to maintain glutathione concentrations.

U2 - 10.1371/journal.pone.0079620

DO - 10.1371/journal.pone.0079620

M3 - Journal article

C2 - 24260265

SN - 1932-6203

VL - 8

SP - e79620

JO - P L o S One

JF - P L o S One

IS - 11

ER -

Glutathione Preservation during Storage of Rat Lenses in Optisol-GS and Castor Oil

Abstract

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