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Region Hovedstaden - en del af Københavns Universitetshospital
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Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network

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  1. Optimization of preprocessing strategies in Positron Emission Tomography (PET) neuroimaging: A [11C]DASB PET study

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  2. Disease-informed brain mapping teaches important lessons about the human brain

    Publikation: Bidrag til tidsskriftLederForskningpeer review

  3. Functional neuroimaging of recovery from motor conversion disorder: A case report

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  4. The role of dopamine in the brain - lessons learned from Parkinson's disease

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  1. European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. No trace of phase: Corticomotor excitability is not tuned by phase of pericentral mu-rhythm

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Altered orbitofrontal sulcogyral patterns in gambling disorder: a multicenter study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Endoscopic surgery requires skilled bimanual use of complex instruments that extend the peri-personal workspace. To delineate brain structures involved in learning such surgical skills, 48 medical students without surgical experience were randomly assigned to five training sessions on a virtual-reality endoscopy simulator or to a non-training group. Brain activity was probed with functional MRI while participants performed endoscopic tasks. Repeated task performance in the scanner was sufficient to enhance task-related activity in left ventral premotor cortex (PMv) and the anterior Intraparietal Sulcus (aIPS). Simulator training induced additional increases in task-related activation in right PMv and aIPS and reduced effective connectivity from left to right PMv. Skill improvement after training scaled with stronger task-related activation of the lateral left primary motor hand area (M1-HAND). The results suggest that a bilateral fronto-parietal grasping network and left M1-HAND are engaged in bimanual learning of tool-based manipulations in an extended peri-personal space.

OriginalsprogEngelsk
TidsskriftNeuroImage
Vol/bind189
Sider (fra-til)32-44
Antal sider13
ISSN1053-8119
DOI
StatusUdgivet - 1 apr. 2019

ID: 55904432