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Region Hovedstaden - en del af Københavns Universitetshospital

Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network

Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  1. Efficient high-resolution TMS mapping of the human motor cortex by nonlinear regression

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  2. Recording brain responses to TMS of primary motor cortex by EEG - utility of an optimized sham procedure

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

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Endoscopic surgery requires skilled bimanual use of complex instruments that extend the peri-personal workspace. To delineate brain structures involved in learning such surgical skills, 48 medical students without surgical experience were randomly assigned to five training sessions on a virtual-reality endoscopy simulator or to a non-training group. Brain activity was probed with functional MRI while participants performed endoscopic tasks. Repeated task performance in the scanner was sufficient to enhance task-related activity in left ventral premotor cortex (PMv) and the anterior Intraparietal Sulcus (aIPS). Simulator training induced additional increases in task-related activation in right PMv and aIPS and reduced effective connectivity from left to right PMv. Skill improvement after training scaled with stronger task-related activation of the lateral left primary motor hand area (M1-HAND). The results suggest that a bilateral fronto-parietal grasping network and left M1-HAND are engaged in bimanual learning of tool-based manipulations in an extended peri-personal space.

Sider (fra-til)32-44
Antal sider13
StatusUdgivet - 1 apr. 2019

ID: 55904432