Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy?

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. No association between early maternal HbA1c and offspring birthweight among women without pre-existing diabetes in Greenland

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Gonorrhoea in Greenland: geographic differences in diagnostic activity and incidence of gonorrhoea in 2015

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Validation of cardiovascular diagnoses in the Greenlandic Hospital Discharge Register for epidemiological use

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Improved survival of head and neck cancer patients in Greenland

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Oncological treatment and outcome of colorectal cancer in Greenland

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Estimates of prediabetes and undiagnosed type 2 diabetes in Denmark: The end of an epidemic or a diagnostic artefact?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Optos wide-field imaging versus conventional camera imaging in Danish patients with type 2 diabetes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Prospective Study of Neuropathic Symptoms Preceding Clinically Diagnosed Diabetic Polyneuropathy: ADDITION-Denmark

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Gestational diabetes mellitus (GDM) is a serious condition associated to both maternal and offspring complications. Yet, no globally accepted consensus exists on how to test and diagnose GDM. In Greenland, the clinical criteria for testing and diagnosing GDM are adapted from Danish guidelines. The aim of this study was to estimate the prevalence of GDM among Greenlanders using both the current clinical GDM criteria and the recent WHO 2013 criteria and, further, to study the association between GDM, pre-pregnant overweight or obesity and macrosomia. A cross-sectional study of all 450 Greenlandic women who gave birth to a singleton in Nuuk within 1 year was performed. Based on an oral glucose tolerance test measuring capillary whole blood glucose, 119 women were categorised as having clinical GDM, WHO 2013 GDM or not GDM. Macrosomia defined as birth weight above 4,000 g was used as outcome variable. The prevalence of clinical GDM and WHO 2013 GDM was 0.4% (95% CI; 0-1.1) and 6.9% (95% CI; 4.5-9.2). WHO 2013 GDM, fasting blood glucose, pre-pregnant maternal overweight and obesity were associated with macrosomia. WHO 2013 GDM criteria were superior to clinical criteria in predicting macrosomia indicating that it may be time to consider the diagnostic strategy used in Greenland. Pre-pregnant overweight may also need more intensified lifestyle-intervention.

ABBREVIATIONS: GDM: Gestational diabetes mellitus; VP: venous plasma; CWB: capillary whole blood; OGTT: oral glucose tolerance test; WHO: World Health Organisation; FIGO: The International Federation of Gynaecology and Obstetrics; BMI: body mass index; GA: gestational age.

OriginalsprogEngelsk
TidsskriftInternational Journal of Circumpolar Health
Vol/bind77
Udgave nummer1
Sider (fra-til)1528126
ISSN1239-9736
DOI
StatusUdgivet - dec. 2018

ID: 55651855