Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination

Keyphrases

• Homologous Recombination 100%
• Chromothripsis 100%
• Retrotransposition 100%
• Germline 100%
• Alu Elements 33%
• Nuclease 33%
• Retrotransposon 33%
• Close Proximity 16%
• Sequence Analysis 16%
• DNA Double-strand Breaks 16%
• Complex Chromosomal Rearrangement 16%
• DNA Repair Capacity 16%
• High-throughput Sequencing 16%
• Chromatin Looping 16%
• Shattering Process 16%
• DNA Cleavage 16%
• Endogenous mutagens 16%

Biochemistry, Genetics and Molecular Biology

• Germline 100%
• Germ Cell 100%
• Homologous Recombination 100%
• Chromothripsis 100%
• Alu Element 33%
• Retrotransposon 33%
• Endonuclease 33%
• DNA Repair 16%
• High Throughput Sequencing 16%
• DNA Cleavage 16%
• Chromatin 16%
• Genomics 16%
• Double-Strand DNA Break 16%