Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Genetics and Individual Predispositions in Contact Dermatitis

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiFormidling

  1. Dermatologisk laserbehandling

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  2. Baggrundsnotat for biologisk behandling af hidrosadenitis suppurativa

    Publikation: Bidrag til udredning/notatBidrag til faglig redegørelse

  3. Quantification of Epidermal Filaggrin in Human Skin and its Response to Skin Irritation

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

Vis graf over relationer
Contact dermatitis cannot develop without exposure to substances in the environment. Conversely, only a part of individuals exposed to the same exogenous stimulus develop contact dermatitis, allergic or irritant. In addition, several cofactors are involved. Hence, the notion of a complex disease, with probably many genes and many environmental factors contributing to the observed phenotypes. There has been a lack of conclusive results in the study of the genetics of allergic and irritant contact dermatitis and, even more, a complete ignorance of the interplay between endogenous factors of individual susceptibility and exposure to noxious agents. In some instances, the environmental factor may override any genetic predisposition. In others, the genetic factor may prevail, with the consequence that the disease is confined to a specific subpopulation, the “noxious agent” doing no harm to the vast majority of people. The endogenous aspects of contact dermatitis and genetics and predisposition related to certain phenotypes are the focus of this chapter.
OriginalsprogEngelsk
TitelContact Dermatitis
RedaktørerJeanne Duus Johansen, Vera Mahler, Jean-Pierre Lepoittevin, Peter J Frosch
Vol/bind1
ForlagSpringer Nature Switzerland AG
Publikationsdato2021
Udgave6
Sider13-52
ISBN (Trykt)978-3-030-36334-5
StatusUdgivet - 2021

ID: 73778146