Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with ischemic heart disease in rheumatoid arthritis

59 Citationer (Scopus)

Abstract

Patients with rheumatoid arthritis (RA) have excess morbidity and mortality due to ischemic heart disease. It has been suggested that high serum levels of mannose-binding lectin (MBL) and agalactosyl IgG (IgG-G0) are associated with increased inflammation in RA. MBL also enhances inflammation-mediated tissue injury during postischemic reperfusion. This study was undertaken to examine whether these factors are associated with increased risk of ischemic heart disease in RA.
OriginalsprogEngelsk
TidsskriftArthritis & Rheumatism
Vol/bind56
Udgave nummer1
Sider (fra-til)21-9
Antal sider9
ISSN0004-3591
DOI
StatusUdgivet - jan. 2007

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