Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters

Marina Grigorova; Margus Punab; Birutė Zilaitienė; Juris Erenpreiss; Kristo Ausmees; Valentinas Matuleviĉius; Igor Tsarev; Niels Jørgensen; Maris Laan

doi:10.1210/jc.2011-0632

Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters

Marina Grigorova
, Margus Punab
, Birutė Zilaitienė
, Juris Erenpreiss
, Kristo Ausmees
, Valentinas Matuleviĉius
, Igor Tsarev
, Niels Jørgensen
, Maris Laan

Afdeling for Vækst og Reproduktion JMC

49 Citationer (Scopus)

Abstract

The detailed role of FSH in contributing to male testicular function and fertility has been debated. We have previously identified the association between the T-allele of the FSHB promoter polymorphism (rs10835638; G/T, -211 bp from the mRNA start) and significantly reduced male serum FSH.

Originalsprog	Engelsk
Tidsskrift	Journal of Clinical Endocrinology and Metabolism
Vol/bind	96
Udgave nummer	9
Sider (fra-til)	E1534-41
ISSN	0021-972X
DOI	https://doi.org/10.1210/jc.2011-0632
Status	Udgivet - 1 sep. 2011

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10.1210/jc.2011-0632

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title = "Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters",

abstract = "The detailed role of FSH in contributing to male testicular function and fertility has been debated. We have previously identified the association between the T-allele of the FSHB promoter polymorphism (rs10835638; G/T, -211 bp from the mRNA start) and significantly reduced male serum FSH.",

author = "Marina Grigorova and Margus Punab and Birutė Zilaitienė and Juris Erenpreiss and Kristo Ausmees and Valentinas Matuleviĉius and Igor Tsarev and Niels J{\o}rgensen and Maris Laan",

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T1 - Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters

AU - Grigorova, Marina

AU - Punab, Margus

AU - Zilaitienė, Birutė

AU - Erenpreiss, Juris

AU - Ausmees, Kristo

AU - Matuleviĉius, Valentinas

AU - Tsarev, Igor

AU - Jørgensen, Niels

AU - Laan, Maris

PY - 2011/9/1

Y1 - 2011/9/1

N2 - The detailed role of FSH in contributing to male testicular function and fertility has been debated. We have previously identified the association between the T-allele of the FSHB promoter polymorphism (rs10835638; G/T, -211 bp from the mRNA start) and significantly reduced male serum FSH.

AB - The detailed role of FSH in contributing to male testicular function and fertility has been debated. We have previously identified the association between the T-allele of the FSHB promoter polymorphism (rs10835638; G/T, -211 bp from the mRNA start) and significantly reduced male serum FSH.

U2 - 10.1210/jc.2011-0632

DO - 10.1210/jc.2011-0632

M3 - Journal article

C2 - 21733993

SN - 0021-972X

VL - 96

SP - E1534-41

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 9

ER -

Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters

Abstract

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