Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome

Marieke J H Coenen, Christian Enevold, Pilar Barrera, Mascha M V A P Schijvenaars, Erik J M Toonen, Hans Scheffer, Leonid Padyukov, Alf Kastbom, Lars Klareskog, Anne Barton, Wietske Kievit, Maarten J Rood, Tim L Jansen, Dorine Swinkels, Piet L C M van Riel, Barbara Franke, Klaus Bendtzen, Timothy R D J Radstake

    27 Citationer (Scopus)

    Abstract

    Several studies point to a role of Toll-like receptors (TLRs) in the development of rheumatoid arthritis (RA). We investigated if genetic variants in TLR genes are associated with RA and response to tumour necrosis factor blocking (anti-TNF) medication.
    OriginalsprogEngelsk
    TidsskriftP L o S One
    Vol/bind5
    Udgave nummer12
    Sider (fra-til)e14326
    ISSN1932-6203
    DOI
    StatusUdgivet - 1 jan. 2010

    Fingeraftryk

    Dyk ned i forskningsemnerne om 'Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome'. Sammen danner de et unikt fingeraftryk.

    Citationsformater