Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects

Trine Holm Johannsen; Ruth Frikke-Schmidt; Jesper Schou; Børge G Nordestgaard; Anne Tybjærg-Hansen

doi:10.1016/j.jacc.2012.07.045

Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects

Trine Holm Johannsen, Ruth Frikke-Schmidt, Jesper Schou, Børge G Nordestgaard, Anne Tybjærg-Hansen

Afdeling for Klinisk Biokemi

129 Citationer (Scopus)

Abstract

This study tested whether genetic variation in the CETP gene is consistent with a protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic events and on total mortality, without the adverse effects reported for torcetrapib.

Originalsprog	Engelsk
Tidsskrift	American College of Cardiology. Journal
Vol/bind	60
Udgave nummer	20
Sider (fra-til)	2041-8
Antal sider	8
ISSN	0735-1097
DOI	https://doi.org/10.1016/j.jacc.2012.07.045
Status	Udgivet - 2012

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10.1016/j.jacc.2012.07.045

Citationsformater

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title = "Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects",

abstract = "This study tested whether genetic variation in the CETP gene is consistent with a protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic events and on total mortality, without the adverse effects reported for torcetrapib.",

author = "Johannsen, {Trine Holm} and Ruth Frikke-Schmidt and Jesper Schou and Nordestgaard, {B{\o}rge G} and Anne Tybj{\ae}rg-Hansen",

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T1 - Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects

AU - Johannsen, Trine Holm

AU - Frikke-Schmidt, Ruth

AU - Schou, Jesper

AU - Nordestgaard, Børge G

AU - Tybjærg-Hansen, Anne

PY - 2012

Y1 - 2012

N2 - This study tested whether genetic variation in the CETP gene is consistent with a protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic events and on total mortality, without the adverse effects reported for torcetrapib.

AB - This study tested whether genetic variation in the CETP gene is consistent with a protective effect of cholesteryl ester transfer protein (CETP) inhibition on risk of ischemic events and on total mortality, without the adverse effects reported for torcetrapib.

U2 - 10.1016/j.jacc.2012.07.045

DO - 10.1016/j.jacc.2012.07.045

M3 - Journal article

C2 - 23083790

SN - 0735-1097

VL - 60

SP - 2041

EP - 2048

JO - American College of Cardiology. Journal

JF - American College of Cardiology. Journal

IS - 20

ER -

Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects

Abstract

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