Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

Børge G Nordestgaard; Anne  Tybjærg-Hansen

doi:10.1097/MOL.0b013e32834477d2

Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

Børge G Nordestgaard, Anne Tybjærg-Hansen

Afdeling for Klinisk Biokemi

53 Citationer (Scopus)

Abstract

To evaluate whether new and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), triglyceride-rich lipoproteins, and HDL cholesterol associate with the risk of cardiovascular disease expected from the effect on lipoprotein levels. Concordance or discordance of such genetic determinants with cardiovascular disease risk will either favor or disfavor that these lipoproteins are causally related to cardiovascular disease.

Originalsprog	Engelsk
Tidsskrift	Current Opinion in Lipidology
Vol/bind	22
Udgave nummer	2
Sider (fra-til)	113-22
Antal sider	10
ISSN	0957-9672
DOI	https://doi.org/10.1097/MOL.0b013e32834477d2
Status	Udgivet - 2011

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10.1097/MOL.0b013e32834477d2

Citationsformater

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title = "Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk",

abstract = "To evaluate whether new and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), triglyceride-rich lipoproteins, and HDL cholesterol associate with the risk of cardiovascular disease expected from the effect on lipoprotein levels. Concordance or discordance of such genetic determinants with cardiovascular disease risk will either favor or disfavor that these lipoproteins are causally related to cardiovascular disease.",

keywords = "Cardiovascular Diseases, Cholesterol, HDL, Humans, Lipoprotein(a), Lipoproteins, Risk Factors",

author = "Nordestgaard, {B{\o}rge G} and Anne Tybj{\ae}rg-Hansen",

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AU - Nordestgaard, Børge G

AU - Tybjærg-Hansen, Anne

PY - 2011

Y1 - 2011

N2 - To evaluate whether new and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), triglyceride-rich lipoproteins, and HDL cholesterol associate with the risk of cardiovascular disease expected from the effect on lipoprotein levels. Concordance or discordance of such genetic determinants with cardiovascular disease risk will either favor or disfavor that these lipoproteins are causally related to cardiovascular disease.

AB - To evaluate whether new and known genetic determinants of plasma levels of LDL cholesterol, lipoprotein(a), triglyceride-rich lipoproteins, and HDL cholesterol associate with the risk of cardiovascular disease expected from the effect on lipoprotein levels. Concordance or discordance of such genetic determinants with cardiovascular disease risk will either favor or disfavor that these lipoproteins are causally related to cardiovascular disease.

KW - Cardiovascular Diseases

KW - Cholesterol, HDL

KW - Humans

KW - Lipoprotein(a)

KW - Lipoproteins

KW - Risk Factors

U2 - 10.1097/MOL.0b013e32834477d2

DO - 10.1097/MOL.0b013e32834477d2

M3 - Journal article

C2 - 21358543

SN - 0957-9672

VL - 22

SP - 113

EP - 122

JO - Current Opinion in Lipidology

JF - Current Opinion in Lipidology

IS - 2

ER -

Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk

Abstract

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