Generelle anæstetikas potentielle neurotoksicitet for den immature hjerne.

Nicola G Clausen, Søren Venø, Mads Astvad, Steen W Henneberg, Kaare Christensen, Tom G Hansen

1 Citationer (Scopus)

Abstract

Animal studies (including non-human primates) have shown that most general anaesthetics cause enhanced neuroapoptosis with subsequent long-term neurocognitive deficits later in life. Some human cohort studies have indicated an association between anaesthesia/surgery and adverse neurocognitive outcome whereas other studies have not. Overall, the data do not justify any change in paediatric anaesthetic clinical practice. Naturally, the risks and benefits of a procedure should always be carefully considered before exposing a child to general anaesthesia.

Bidragets oversatte titelPotential neurotoxicty of general anaesthetics to the developing brain.
OriginalsprogDansk
TidsskriftUgeskrift for læger [online]
Vol/bind176
Udgave nummer34
ISSN1603-6824
StatusUdgivet - 18 aug. 2014

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