Gene expression in the neuropeptide Y system during ethanol withdrawal kindling in rats

Janne Damm Olling; Jakob Ulrichsen; Mette Correll; David P D Woldbye

doi:10.1111/j.1530-0277.2009.01110.x

Gene expression in the neuropeptide Y system during ethanol withdrawal kindling in rats

Janne Damm Olling, Jakob Ulrichsen, Mette Correll, David P D Woldbye

3 Citationer (Scopus)

Abstract

Multiple episodes of ethanol intoxication and withdrawal result in progressive, irreversible intensification of the withdrawal reaction, a process termed "ethanol withdrawal kindling." Previous studies show that a single episode of chronic ethanol intoxication and withdrawal causes prominent changes in neuropeptide Y (NPY) and its receptors that have been implicated in regulating withdrawal hyperexcitability. This study for the first time examined the NPY system during ethanol withdrawal kindling.

Originalsprog	Engelsk
Tidsskrift	Alcoholism: Clinical and Experimental Research
Vol/bind	34
Udgave nummer	3
Sider (fra-til)	462-70
Antal sider	9
ISSN	0145-6008
DOI	https://doi.org/10.1111/j.1530-0277.2009.01110.x
Status	Udgivet - 1 mar. 2010

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10.1111/j.1530-0277.2009.01110.x

Citationsformater

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AU - Olling, Janne Damm

AU - Ulrichsen, Jakob

AU - Correll, Mette

AU - Woldbye, David P D

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Multiple episodes of ethanol intoxication and withdrawal result in progressive, irreversible intensification of the withdrawal reaction, a process termed "ethanol withdrawal kindling." Previous studies show that a single episode of chronic ethanol intoxication and withdrawal causes prominent changes in neuropeptide Y (NPY) and its receptors that have been implicated in regulating withdrawal hyperexcitability. This study for the first time examined the NPY system during ethanol withdrawal kindling.

AB - Multiple episodes of ethanol intoxication and withdrawal result in progressive, irreversible intensification of the withdrawal reaction, a process termed "ethanol withdrawal kindling." Previous studies show that a single episode of chronic ethanol intoxication and withdrawal causes prominent changes in neuropeptide Y (NPY) and its receptors that have been implicated in regulating withdrawal hyperexcitability. This study for the first time examined the NPY system during ethanol withdrawal kindling.

U2 - 10.1111/j.1530-0277.2009.01110.x

DO - 10.1111/j.1530-0277.2009.01110.x

M3 - Journal article

C2 - 20028355

SN - 0145-6008

VL - 34

SP - 462

EP - 470

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

IS - 3

ER -

Gene expression in the neuropeptide Y system during ethanol withdrawal kindling in rats

Abstract

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