Gene expression and 18FDG uptake in atherosclerotic carotid plaques

Sune Folke Pedersen; Martin Græbe; Anne Mette Fisker Hag; Liselotte Højgaard; Henrik Hegaard Sillesen; Andreas Kjær

doi:10.1097/MNM.0b013e32833767e0

Gene expression and 18FDG uptake in atherosclerotic carotid plaques

Sune Folke Pedersen, Martin Græbe, Anne Mette Fisker Hag, Liselotte Højgaard, Henrik Hegaard Sillesen, Andreas Kjær

Afdeling for Klinisk Fysiologi og Nuklearmedicin DIA

98 Citationer (Scopus)

Abstract

Metabolic assessment of vascular inflammation by 2-[F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG)-PET is a promising new approach for the evaluation of the vulnerability of atherosclerotic plaques. Quantitative real-time PCR allows measurement of gene expression of markers of atherosclerotic plaque vulnerability. These techniques were applied in advanced atherosclerotic disease to relate metabolism and inflammatory activity to the gene expression profile of the vulnerable atherosclerotic plaque.

Originalsprog	Engelsk
Tidsskrift	Nuclear Medicine Communications
Vol/bind	31
Udgave nummer	5
Sider (fra-til)	423-9
Antal sider	7
ISSN	0143-3636
DOI	https://doi.org/10.1097/MNM.0b013e32833767e0
Status	Udgivet - 1 maj 2010

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AU - Pedersen, Sune Folke

AU - Græbe, Martin

AU - Hag, Anne Mette Fisker

AU - Højgaard, Liselotte

AU - Sillesen, Henrik Hegaard

AU - Kjær, Andreas

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N2 - Metabolic assessment of vascular inflammation by 2-[F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG)-PET is a promising new approach for the evaluation of the vulnerability of atherosclerotic plaques. Quantitative real-time PCR allows measurement of gene expression of markers of atherosclerotic plaque vulnerability. These techniques were applied in advanced atherosclerotic disease to relate metabolism and inflammatory activity to the gene expression profile of the vulnerable atherosclerotic plaque.

AB - Metabolic assessment of vascular inflammation by 2-[F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG)-PET is a promising new approach for the evaluation of the vulnerability of atherosclerotic plaques. Quantitative real-time PCR allows measurement of gene expression of markers of atherosclerotic plaque vulnerability. These techniques were applied in advanced atherosclerotic disease to relate metabolism and inflammatory activity to the gene expression profile of the vulnerable atherosclerotic plaque.

UR - https://www.scopus.com/pages/publications/77951079412

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SP - 423

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Gene expression and 18FDG uptake in atherosclerotic carotid plaques

Abstract

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