Gastrointestinal complications after fast-track total hip and knee replacement: an observational study in a consecutive 36,932 patient cohort

Louise O.H. Daugberg*, Henrik Kehlet, Pelle B. Petersen, Thomas Jakobsen, Christoffer C. Jørgensen, The Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement collaborative Group, Frank Madsen (Medlem af forfattergruppering), Torben Bæk Hansen (Medlem af forfattergruppering), Kirill Gromov (Medlem af forfattergruppering), Lars Tambour Hansen (Medlem af forfattergruppering), Claus Varnum (Medlem af forfattergruppering), Mikkel Rathsach Andersen (Medlem af forfattergruppering), Niels Harry Krarup (Medlem af forfattergruppering), Søren Overgaard (Medlem af forfattergruppering)

*Corresponding author af dette arbejde


INTRODUCTION: Gastrointestinal complications after total hip (THA) and knee arthroplasty (TKA) have been reported to be between 0.3 and 2.6% with bleeding and C. difficile infection in 0-1%, and 0.1-1.7%, respectively. The use of enhanced recovery or "fast-track" protocols have focused on optimizing all aspects of perioperative care resulting in reduced length of hospital stay (LOS) and potentially also gastrointestinal complications. This study is a detailed analysis on the occurrence of postoperative gastrointestinal complications resulting in increased hospital stay or readmissions in a large consecutive cohort of fast-track THA and TKA with complete 90 days follow-up.

MATERIALS AND METHODS: This is an observational study on a consecutive cohort of primary unilateral THAs and TKAs performed between January 2010 and August 2017 in nine Danish high-volume fast-track centers. Discharge summaries and relevant patient records were reviewed in patients with readmissions within 90 days or LOS > 4 days caused by gastrointestinal complications.

RESULTS: The cohort included 36,932 patients with 58.3% females and 54.1% THAs. Mean age and BMI were 68 years and 28. Median postoperative LOS was 2 days. Only n: 276 (0.75 %) had a LOS > 4 days or a readmission within 90 days due to a gastrointestinal complication (CI 0.67%-0.84%). Of these, only 34 (0.09%) were graded as severe ileus or gastrointestinal bleeding.

CONCLUSIONS: The risk of GI-complications within the first 90 postoperative days after fast-track THA and TKA was low (0.75%).

TidsskriftArchives of Orthopaedic and Trauma Surgery
Udgave nummer10
Sider (fra-til)6033-6038
Antal sider6
StatusUdgivet - okt. 2023


Dyk ned i forskningsemnerne om 'Gastrointestinal complications after fast-track total hip and knee replacement: an observational study in a consecutive 36,932 patient cohort'. Sammen danner de et unikt fingeraftryk.