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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Gamma-glutamyltransferase, aspartate aminotransferase and alkaline phosphatase as markers of alcohol consumption in out-patient alcoholics

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  • C Gluud
  • I Andersen
  • O Dietrichson
  • B Gluud
  • A Jacobsen
  • E Juhl
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Serum activity of gamma-glutamyltransferase, aspartate aminotransferase and alkaline phosphatase were determined in 316 patients attending an out-patients clinic for treatment of alcoholism. The activity of gamma-glutamyltransferase was raised in 34% and that of aspartate aminotransferase and alkaline phosphatase in 18% and 7%. Neither the activity of gamma-glutamyltransferase, aspartate aminotransferase nor alkaline phosphatase showed any significant (P greater than 0.05) correlation with the history of alcohol consumption. The activities of gamma-glutamyltransferase and aspartate aminotransferase were raised significantly more often in patients with recent alcohol consumption than in patients who had abstained for more than 9 days. The concentration of alkaline phosphatase was not significantly (P greater than 0.05) different in these groups. The predictive value of raised and normal activities of gamma-glutamyltransferase, in deciding whether a patient had had recent alcohol consumption or not, was not superior to the predictive value of raised and normal activities of aspartate aminotransferase.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Clinical Investigation
Vol/bind11
Udgave nummer3
Sider (fra-til)171-6
Antal sider6
ISSN0014-2972
StatusUdgivet - jun. 1981

ID: 38929602