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GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Harvard
Belhage, B, Hansen, GH, Schousboe, A & Meier, E 1988, 'GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development' International Journal of Developmental Neuroscience, bind 6, nr. 2, s. 125-8.
APA
Belhage, B., Hansen, G. H., Schousboe, A., & Meier, E. (1988). GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development. International Journal of Developmental Neuroscience, 6(2), 125-8.
CBE
Belhage B, Hansen GH, Schousboe A, Meier E. 1988. GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development. International Journal of Developmental Neuroscience. 6(2):125-8.
MLA
Belhage, B o.a.. "GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development". International Journal of Developmental Neuroscience. 1988, 6(2). 125-8.
Vancouver
Belhage B, Hansen GH, Schousboe A, Meier E. GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development. International Journal of Developmental Neuroscience. 1988 jan 1;6(2):125-8.
Author
Bibtex
@article{e7f98649b5dd48348ce6cd7d3ef4dbb6,
title = "GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development",
abstract = "The ability of the GABA receptor agonist 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) to promote formation of low affinity GABA receptors on cerebellar granule cells was tested using primary cultures of these neurons. Granule cells were exposed to THIP (150 microM) for 6 hr after, respectively, 4, 7, 10 and 14 days in culture. It was found that THIP treatment of 4- and 7-day-old cultures led to formation of low affinity GABA receptors, whereas such receptors could not be detected after THIP treatment in the older cultures (10 and 14 days) in spite of the fact that these cultured granule cells expressed a high density of high affinity GABA receptors. It is concluded that the ability of THIP to promote formation of low affinity GABA receptors on cerebellar granule cells is restricted to an early developmental period.",
author = "B Belhage and Hansen, {G H} and A Schousboe and E Meier",
year = "1988",
month = "1",
day = "1",
language = "English",
volume = "6",
pages = "125--8",
journal = "International Journal of Developmental Neuroscience",
issn = "0736-5748",
publisher = "Pergamon",
number = "2",
}
RIS
TY - JOUR
T1 - GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development
AU - Belhage, B
AU - Hansen, G H
AU - Schousboe, A
AU - Meier, E
PY - 1988/1/1
Y1 - 1988/1/1
N2 - The ability of the GABA receptor agonist 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) to promote formation of low affinity GABA receptors on cerebellar granule cells was tested using primary cultures of these neurons. Granule cells were exposed to THIP (150 microM) for 6 hr after, respectively, 4, 7, 10 and 14 days in culture. It was found that THIP treatment of 4- and 7-day-old cultures led to formation of low affinity GABA receptors, whereas such receptors could not be detected after THIP treatment in the older cultures (10 and 14 days) in spite of the fact that these cultured granule cells expressed a high density of high affinity GABA receptors. It is concluded that the ability of THIP to promote formation of low affinity GABA receptors on cerebellar granule cells is restricted to an early developmental period.
AB - The ability of the GABA receptor agonist 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) to promote formation of low affinity GABA receptors on cerebellar granule cells was tested using primary cultures of these neurons. Granule cells were exposed to THIP (150 microM) for 6 hr after, respectively, 4, 7, 10 and 14 days in culture. It was found that THIP treatment of 4- and 7-day-old cultures led to formation of low affinity GABA receptors, whereas such receptors could not be detected after THIP treatment in the older cultures (10 and 14 days) in spite of the fact that these cultured granule cells expressed a high density of high affinity GABA receptors. It is concluded that the ability of THIP to promote formation of low affinity GABA receptors on cerebellar granule cells is restricted to an early developmental period.
M3 - Journal article
VL - 6
SP - 125
EP - 128
JO - International Journal of Developmental Neuroscience
JF - International Journal of Developmental Neuroscience
SN - 0736-5748
IS - 2
ER -
ID: 32359169