Functional recovery after experimental RPE debridement, mfERG studies in a porcine model

Nina Buus Sørensen; Nathan Lassota; Maria Voss Kyhn; Jan Ulrik Prause; Klaus Qvortrup; Morten la Cour; Jens Kiilgaard

doi:10.1007/s00417-013-2331-6

Functional recovery after experimental RPE debridement, mfERG studies in a porcine model

Nina Buus Sørensen, Nathan Lassota, Maria Voss Kyhn, Jan Ulrik Prause, Klaus Qvortrup, Morten la Cour, Jens Kiilgaard

Afdeling for Øjensygdomme

12 Citationer (Scopus)

Abstract

The correlation between histologically identified regeneration of retinal pigment epithelium (RPE) and functional outcome measured by multifocal electroretinography (mfERG) following surgical debridement is examined in a porcine model. In humans, visual acuity is reduced in diseases with RPE loss such as RPE tears and geographic atrophy. Hypopigmented RPE is known to cover the lesion after RPE debridement in the pig, but it is unclear whether this leads to a return of photoreceptor function.

Originalsprog	Engelsk
Tidsskrift	Graefe's Archive for Clinical and Experimental Ophthalmology
Vol/bind	251
Udgave nummer	10
Sider (fra-til)	2319-25
Antal sider	7
ISSN	0721-832X
DOI	https://doi.org/10.1007/s00417-013-2331-6
Status	Udgivet - okt. 2013

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10.1007/s00417-013-2331-6

Citationsformater

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abstract = "The correlation between histologically identified regeneration of retinal pigment epithelium (RPE) and functional outcome measured by multifocal electroretinography (mfERG) following surgical debridement is examined in a porcine model. In humans, visual acuity is reduced in diseases with RPE loss such as RPE tears and geographic atrophy. Hypopigmented RPE is known to cover the lesion after RPE debridement in the pig, but it is unclear whether this leads to a return of photoreceptor function.",

author = "S{\o}rensen, {Nina Buus} and Nathan Lassota and Kyhn, {Maria Voss} and Prause, {Jan Ulrik} and Klaus Qvortrup and {la Cour}, Morten and Jens Kiilgaard",

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T1 - Functional recovery after experimental RPE debridement, mfERG studies in a porcine model

AU - Sørensen, Nina Buus

AU - Lassota, Nathan

AU - Kyhn, Maria Voss

AU - Prause, Jan Ulrik

AU - Qvortrup, Klaus

AU - la Cour, Morten

AU - Kiilgaard, Jens

PY - 2013/10

Y1 - 2013/10

N2 - The correlation between histologically identified regeneration of retinal pigment epithelium (RPE) and functional outcome measured by multifocal electroretinography (mfERG) following surgical debridement is examined in a porcine model. In humans, visual acuity is reduced in diseases with RPE loss such as RPE tears and geographic atrophy. Hypopigmented RPE is known to cover the lesion after RPE debridement in the pig, but it is unclear whether this leads to a return of photoreceptor function.

AB - The correlation between histologically identified regeneration of retinal pigment epithelium (RPE) and functional outcome measured by multifocal electroretinography (mfERG) following surgical debridement is examined in a porcine model. In humans, visual acuity is reduced in diseases with RPE loss such as RPE tears and geographic atrophy. Hypopigmented RPE is known to cover the lesion after RPE debridement in the pig, but it is unclear whether this leads to a return of photoreceptor function.

U2 - 10.1007/s00417-013-2331-6

DO - 10.1007/s00417-013-2331-6

M3 - Journal article

C2 - 23575950

SN - 0721-832X

VL - 251

SP - 2319

EP - 2325

JO - Graefe's Archive for Clinical and Experimental Ophthalmology

JF - Graefe's Archive for Clinical and Experimental Ophthalmology

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ER -

Functional recovery after experimental RPE debridement, mfERG studies in a porcine model

Abstract

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