Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

Sven Jarius, Jette Lautrup Battistini Frederiksen, Patrick Waters, Friedemann Paul, Gulsen Akman-Demir, Romain Marignier, Diego Franciotta, Klemens Ruprecht, Bettina Kuenz, Paulus Rommer, Wolfgang Kristoferitsch, Brigitte Wildemann, Angela Vincent

155 Citationer (Scopus)

Abstract

Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord.
OriginalsprogEngelsk
TidsskriftJournal of the Neurological Sciences
Vol/bind298
Udgave nummer1-2
Sider (fra-til)158-62
Antal sider5
DOI
StatusUdgivet - 15 nov. 2010

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