TY - JOUR
T1 - Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage
AU - Nielsen, Henriette Svarre
AU - Steffensen, Rudi Nora
AU - Lund, Marie
AU - Egestad, Lisbeth
AU - Mortensen, Laust Hvas
AU - Andersen, Anne-Marie Nybo
AU - Lidegaard, Ø
AU - Christiansen, O B
PY - 2010/6/1
Y1 - 2010/6/1
N2 - The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
AB - The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
U2 - 10.1093/humrep/deq091
DO - 10.1093/humrep/deq091
M3 - Journal article
C2 - 20395221
VL - 25
SP - 1543
EP - 1552
JO - Human Reproduction
JF - Human Reproduction
SN - 0268-1161
IS - 6
ER -