Abstract
In order to evaluate the association between male subfertility and the subsequent risk of testicular cancer, a population-based case-control study was conducted in The Danish population. Cases were identified in the Danish Cancer Registry; controls were randomly selected from the Danish population using the computerized Danish Central Population Register. The men were interviewed by telephone; 514 cases and 720 controls participated. A reduced risk of testicular cancer was associated with paternity (relative risk = 0.63; 95% confidence interval: 0.47-0.85). In men who prior to the diagnosis of testicular cancer had a lower number of children than expected on the basis of their age, the relative risk was 1.98 (95% confidence interval: 1.43-2.75). There was no corresponding protective effect associated with a higher number of children than expected. The associations were similar for seminoma and non-seminoma, and were not influenced by adjustment for potential confounding factors. These data are consistent with the hypothesis that male subfertility and testicular cancer share important aetiological factors.
Bidragets oversatte titel | Occurrence of testicular cancer in subfertile men. A case-control study |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 161 |
Udgave nummer | 47 |
Sider (fra-til) | 6490-2 |
Antal sider | 3 |
ISSN | 0041-5782 |
Status | Udgivet - 22 nov. 1999 |
Udgivet eksternt | Ja |
Emneord
- Adult
- Aged
- Case-Control Studies
- Denmark/epidemiology
- Humans
- Infertility, Male/complications
- Male
- Middle Aged
- Registries
- Risk Factors
- Surveys and Questionnaires
- Testicular Neoplasms/epidemiology