TY - JOUR
T1 - Food & Fertility Study
T2 - study protocol for a Danish multicentre prospective cohort study investigating the association between food intake and semen quality, pregnancy and birth outcomes in infertile women and men
AU - Buhl Borgstrøm, Maria
AU - Ahrendt Bjerregaard, Anne
AU - Olsen, Sjurdur F
AU - Gabrielsen, Anette
AU - Humaidan, Peter
AU - Kesmodel, Ulrik Schiøler
N1 - © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2023/7/4
Y1 - 2023/7/4
N2 - INTRODUCTION: Worldwide infertility is highly prevalent, and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment. The literature is not consistent and adequate for recommendations to the increasing number of women and men of reproductive age who ask for lifestyle guidance. Therefore, the aims of the Food & Fertility Study will be to investigate the possible association between food intake and semen quality in men, and pregnancy and live birth rates in women undergoing intrauterine insemination or assisted reproductive technology treatment.METHODS AND ANALYSIS: The Food & Fertility Study is a multicentre prospective cohort study which plans to enrol a total of 4000 women and men between 2022 and 2024. Data collection will take place in four fertility clinics through a web-based Food Frequency Questionnaire. Data on sperm quality and pregnancy and live birth rates will be obtained from medical records and national registers.ETHICS AND DISSEMINATION: The study is registered with and approved by the Danish Data Protection Agency, the North Denmark Region (j.nr: 2019-055298). Further, a Statement of Work and a Master Collaboration Agreement have been submitted and approved by the regional legal departments (AGR-2019-731-9667). Dissemination of the results will be through national and international conferences, in scientific environments, in the form of lectures to the broader public, and by peer-reviewed publications in international scientific journals.TRIAL REGISTRATION NUMBER: NCT05454046.
AB - INTRODUCTION: Worldwide infertility is highly prevalent, and lifestyle factors, such as food intake, could have an essential role in the success of a fertility treatment. The literature is not consistent and adequate for recommendations to the increasing number of women and men of reproductive age who ask for lifestyle guidance. Therefore, the aims of the Food & Fertility Study will be to investigate the possible association between food intake and semen quality in men, and pregnancy and live birth rates in women undergoing intrauterine insemination or assisted reproductive technology treatment.METHODS AND ANALYSIS: The Food & Fertility Study is a multicentre prospective cohort study which plans to enrol a total of 4000 women and men between 2022 and 2024. Data collection will take place in four fertility clinics through a web-based Food Frequency Questionnaire. Data on sperm quality and pregnancy and live birth rates will be obtained from medical records and national registers.ETHICS AND DISSEMINATION: The study is registered with and approved by the Danish Data Protection Agency, the North Denmark Region (j.nr: 2019-055298). Further, a Statement of Work and a Master Collaboration Agreement have been submitted and approved by the regional legal departments (AGR-2019-731-9667). Dissemination of the results will be through national and international conferences, in scientific environments, in the form of lectures to the broader public, and by peer-reviewed publications in international scientific journals.TRIAL REGISTRATION NUMBER: NCT05454046.
KW - Female
KW - Humans
KW - Male
KW - Pregnancy
KW - Denmark/epidemiology
KW - Eating
KW - Infertility, Female/therapy
KW - Multicenter Studies as Topic
KW - Prospective Studies
KW - Semen
KW - Semen Analysis
UR - http://www.scopus.com/inward/record.url?scp=85163995361&partnerID=8YFLogxK
U2 - 10.1136/bmjopen-2022-068354
DO - 10.1136/bmjopen-2022-068354
M3 - Journal article
C2 - 37407049
SN - 2044-6055
VL - 13
SP - e068354
JO - BMJ Open
JF - BMJ Open
IS - 7
M1 - e068354
ER -