Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Focal cerebral hyperemia in acute stroke. Incidence, pathophysiology and clinical significance

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Cardiac Troponin I and Incident Stroke in European Cohorts: Insights From the BiomarCaRE Project

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke: The Global COVID-19 Stroke Registry

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Incidence of Ischemic Stroke in Individuals With and Without Aortic Valve Stenosis: A Danish Retrospective Cohort Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Global Burden of Small Vessel Disease-Related Brain Changes on MRI Predicts Cognitive and Functional Decline

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Vestibularis-schwannomers diagnostik og vaekst bedømt ved SPECT kombineret med TL-201 Thallium

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Activation-induced resetting of cerebral oxygen and glucose uptake in the rat

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Activation-induced resetting of cerebral oxygen and glucose uptak in the rat

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. SPECT og PET i neurobiologien

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • T S Olsen
  • B Larsen
  • E B Skriver
  • M Herning
  • E Enevoldsen
  • N A Lassen
Vis graf over relationer
In a consecutive study comprising 41 patients with completed stroke of less than 72 hours duration, cerebral angiography and measurements of the regional cerebral blood flow (rCBF) were performed within 24 hours after admission. The rCBF study was done using the 133-Xenon intracarotid injection method and a 254 multi-detector camera. CT scan was done 24 hours after the rCBF study. Focal cerebral hyperemia was found in 16 patients. The study revealed 3 different types of hyperemia: Border-zone hyperemia, surrounding ischemic areas, was seen in patients with occluded arteries on angiography, presumably resulting from accumulation of acid metabolites in the border-zone of acute infarcts. Postischemic hyperemia was seen in patients without occlusion, presumably due to recanalization of a prior occluded artery. Remote hyperemia was found distant from the infarcted area, presumably due to local tissue pressure on brain tissue. Cortical infarcts (10 patients) all had extensive hyperemic areas. Because the 254 detector camera has an excellent resolution in the cortical surface, our findings strongly suggest that all acute cerebral infarcts are, in fact, associated with hyperemic areas. The hyperemic areas are often extensive and vascular reactivity is commonly impaired. It is suggested that treatment aimed at reducing blood flow in hyperemic areas might improve prognosis.
OriginalsprogEngelsk
TidsskriftStroke
Vol/bind12
Udgave nummer5
Sider (fra-til)598-607
Antal sider10
ISSN0039-2499
StatusUdgivet - 1981

ID: 39051852