Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Søren Astrup Jensen; Philip Hasbak; Jann Mortensen; Jens Benn Sørensen

doi:10.1200/JCO.2009.27.3953

Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Søren Astrup Jensen, Philip Hasbak, Jann Mortensen, Jens Benn Sørensen

Afdeling for Klinisk Fysiologi og Nuklearmedicin DIA

92 Citationer (Scopus)

Abstract

Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.

Originalsprog	Engelsk
Tidsskrift	Journal of Clinical Oncology
Vol/bind	28
Udgave nummer	36
Sider (fra-til)	5280-6
Antal sider	7
ISSN	0732-183X
DOI	https://doi.org/10.1200/JCO.2009.27.3953
Status	Udgivet - 20 dec. 2010

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Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle. / Jensen, Søren Astrup; Hasbak, Philip ; Mortensen, Jann et al.
I: Journal of Clinical Oncology, Bind 28, Nr. 36, 20.12.2010, s. 5280-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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title = "Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle",

abstract = "Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.",

author = "Jensen, \{S{\o}ren Astrup\} and Philip Hasbak and Jann Mortensen and S{\o}rensen, \{Jens Benn\}",

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T1 - Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

AU - Jensen, Søren Astrup

AU - Hasbak, Philip

AU - Mortensen, Jann

AU - Sørensen, Jens Benn

PY - 2010/12/20

Y1 - 2010/12/20

N2 - Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.

AB - Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.

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U2 - 10.1200/JCO.2009.27.3953

DO - 10.1200/JCO.2009.27.3953

M3 - Journal article

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SN - 0732-183X

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JO - Journal of Clinical Oncology

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Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Abstract

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