Fluorouracil induces myocardial ischemia with increases of plasma brain natriuretic peptide and lactic acid but without dysfunction of left ventricle

Søren Astrup Jensen, Philip Hasbak, Jann Mortensen, Jens Benn Sørensen

82 Citationer (Scopus)

Abstract

Fluorouracil (FU) is a cornerstone of colorectal cancer treatment; however, it has clinical and subclinical influence on the heart. This study aimed to clarify the pathophysiology, risk factors, and long-term effects of FU cardiotoxicity.
OriginalsprogEngelsk
TidsskriftJournal of Clinical Oncology
Vol/bind28
Udgave nummer36
Sider (fra-til)5280-6
Antal sider7
ISSN0732-183X
DOI
StatusUdgivet - 20 dec. 2010

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